How much is Zepbound with or without insurance?
Zepbound may cost $25 for a 1-month or 3-month pen prescription if you have insurance and eligible for the Savings card, but without insurance, Zepbound can cost $349 for a 2.5mg vial and $499 for a 5mg vial through LillyDirect for a 1-month prescription. Without insurance, the cost of Zepbound pens varies depending on the pharmacy and any discounts or patient assistance programs you use.
Zepbound cost with insurance
Zepbound costs $25 for a 1-month or 3-month prescription if you have commercial insurance and a Zepbound savings card. This saving card covers single-dose pens 2.5 mg, 5 mg, 7.5mg, 10 mg, 12.5 mg, and 15 mg doses and is available in pharmacies and through LillyDirect Pharmacy Solutions.
Read more: What is the Zepbound Coupon or Savings Card?
Zepbound cost without insurance
The cost of Zepbound without insurance is $349 for a 2.5mg vial, $499 for a 5mg vial, for a one-month prescription from LillyDirect self-pay pharmacy.
The Zepbound Self Pay Journey Program allows you to receive automatic savings on 7.5 and 10 mg doses $499 per month if you refill within 45 days of your prior delivery. 1-month supply is defined as 28 days and 4 vials. Additional taxes and fees may apply.
You can usually save money using the Zepbound vials instead of the Zepbound pens. Single-dose vials are administered using a needle and a syringe.
Zepbound pen costs vary from different pharmacies and can be checked on the Zepbound Prices, Coupons, Copay Cards & Patient Assistance page.
See Zepbound Savings Card Program Terms and Conditions for more information.
References
How much should I expect to pay for Zepbound® (tirzepatide)? [accessed on August 19, 2025] https://pricinginfo.lilly.com/zepbound
Zepbound Saving Options Including Terms and Conditions. Accessed August 19, 2025.https://zepbound.lilly.com/coverage-savings
Read next
Zepbound vs Mounjaro: Comparison Guide for Weight Loss and Diabetes Treatment
Zepbound and Mounjaro contain the same active ingredient (tirzepatide) and both are made by Eli Lilly and Company, but they have different FDA approved uses and insurance coverage. Zepbound is approved for chronic weight management and obstructive sleep apnea (OSA) and Mounjaro is approved for type 2 diabetes.
Continue reading
Ozempic Mounjaro Wegovy & Zepbound: Weight Loss Compared
Ozempic, Mounjaro, Wegovy and Zepbound can all lead to long-term weight loss, but only Wegovy and Zepbound are approved by the FDA for this use. In studies, Zepbound has led to a 21% weight loss in adults using the highest dose, while Wegovy has led to about a 15% weight loss.
Continue reading
Which GLP-1 drug is best for weight loss?
The most effective GLP-1 drug for weight loss currently (as of mid-2025) is tirzepatide, marketed under the names Zepbound (for weight loss) and Mounjaro (for diabetes).
Continue readingSee also:
Related medical questions
- How long does it take for Zepbound to work?
- Can you get tirzepatide from a compounding pharmacy?
- How do Zepbound and Wegovy compare?
- Is Zepbound covered by insurance?
- How much weight can I lose on Zepbound?
- What happens when you stop taking Zepbound?
- Why can Zepbound cause headaches and what to do about it?
- Why am I not losing weight on Zepbound​?
- How does Zepbound help with sleep apnea?
- How do you inject / administer Zepbound?
- MariTide vs Wegovy or Zepbound: how do they compare?
- How do I know if I have sleep apnea? The warning signs
- What is the Zepbound Coupon or Savings Card?
- Is sleep apnea the hidden cause of your high blood pressure?
- Can sleep apnea kill you? Understanding the real risks?
- Can Zepbound and Mounjaro be used for heart failure?
Drug information
Related support groups
- Zepbound (23 questions, 30 members)
- Tirzepatide (19 questions, 15 members)
- Weight Loss (Obesity/Overweight) (877 questions, 1,514 members)