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What is Vaxchora used for?

Medically reviewed by Judith Stewart, BPharm. Last updated on Feb 13, 2024.

Official answer


Vaxchora (Cholera Vaccine, Live, Oral) is an oral vaccine indicated for active immunization against cholera.

What is Vaxchora?

Vaxchora is a live, weakened vaccine that is taken as a single, oral liquid dose at least 10 days before travel to a cholera-affected area.

What is Cholera?

Cholera is a disease caused by Vibrio cholerae bacteria that is acquired by ingesting contaminated water or food. It causes watery diarrhea that can range from mild to extremely severe. Severe cholera is characterized by profuse diarrhea and vomiting, leading to dehydration. It can be fatal if rehydration treatment is not initiated promptly.

How is Cholera prevented?

The CDC recommends that adults traveling to areas with active cholera transmission get vaccinated with Vaxchora.

Vaxchora is administered orally as a single dose of approximately 100 mL at least 10 days before potential exposure to cholera. Travelers should also follow CDC recommendations for cholera-prevention including safe food and water practices, and frequent hand washing.

  • Centers for Disease Control and Prevention. Cholera Information for Travelers. Available at [Accessed February 23, 2021]
  • U.S. Food and Drug Administration. VAXCHORA Product Label. Available at [Accessed February 23, 2021]

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