Is Truxima a chemotherapy drug?
Truxima (rituximab-abbs) is not a chemotherapy drug, rather it is a biologic that is targeted toward specific antigens (proteins). In this case, Truxima targets the CD20 antigen expressed on the surface of pre-B and mature B-lymphocytes. Truxima forms a complex with the CD20 antigen which causes B-cell death (lysis). Most cases of non-Hodgkin’s lymphoma and chronic lymphocytic leukemia arise from B cells. Truxima is usually used together with chemotherapy treatments.
References
- Truxima (rituximab-abbs) Updated Feb 1, 2022 [Product Information] https://www.drugs.com/pro/truxima.html
Read next
What are biosimilar drugs and how do they compare to biologics?
A biosimilar is a biological product that is similar to a reference biologic (usually the originally approved product) and for which there are no clinically meaningful differences in terms of safety, purity, and potency. The most recently approved biosimilar is Starjemza (ustekinumab-hmny), an interchangeable biosimilar to Stelara, cleared by the FDA on May 22, 2025.
Continue reading
What is the difference between Truxima and Rituxan?
Truxima (rituximab-abbs) is a biosimilar to Rituxan (rituximab). While both drugs are CD20-directed cytolytic antibodies used to treat non-Hodgkin’s lymphoma (NHL), Rituxan has additional FDA-approved indications beyond NHL. Continue reading
Does Truxima make you gain weight?
Weight gain has been reported in 11% of patients being treated with Truxima (rituximab) for non-Hodgkin’s lymphoma (NHL). Be sure to contact your doctor right away if you have a rapid or unexplained weight gain or fluid retention (edema), nausea, vomiting, diarrhea, or lack of energy when using Truxima, as you may need immediate medical care. Continue reading
See also:
Aimovig
Learn about Aimovig (erenumab-aooe) a once-monthly, injectable medication that can be ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Imbruvica
Imbruvica (ibrutinib) is used to treat chronic lymphocytic leukemia (CLL), small lymphocytic ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Emgality
Emgality (galcanezumab-gnlm) is a CGRP antagonist for the preventive treatment of migraine and for ...
Inderal
Inderal (propranolol) is used to treat angina, high blood pressure and heart rhythm disorders ...
Ajovy
Ajovy (fremanezumab-vfrm) is a preventive migraine treatment. Includes Ajovy side effects ...
Vyepti
Vyepti (eptinezumab-jjmr) is used for the preventive treatment of migraine. Includes Vyepti ...
Botox Cosmetic
Botox Cosmetic is a prescription treatment for fine lines and wrinkles. It temporarily improves the ...
Fremanezumab
Fremanezumab is used for chronic migraine, headache, migraine, migraine prevention
Related medical questions
- What biosimilars have been approved in the United States?
- What are the new drugs for rheumatoid arthritis (RA)?
- How soon can you start chemo after port placement?
- What is the success rate of Rituxan (rituximab) in patients with blood cancers?
- What is the success rate of Rituxan (rituximab) in rheumatoid arthritis?
- What causes infusion reactions to rituximab?
- What is the difference between Rituxan and Rituxan Hycela?
- What are biologic drugs and how do they work?
- Are lung nodules common after Bendeka & Rituxan therapy?
- How will I feel after a Rituxan infusion?
- How long does it take for Rituxan to work?
- How does the drug Rituxan work?
- Is Venclexta (venetoclax) chemotherapy?
- How do you prepare for a Rituxan infusion?
- How effective is Venclexta?
- How long do you take Venclexta for?
- Does ibrutinib cause hair loss?
- What are the names of the BTK inhibitors?
- How is Bendeka different to Treanda?
- How is Arzerra administered and how long to work?
- What is Arzerra used for and how does it work?
- Is Zydelig a chemotherapy drug?
- What is Zydelig used for and how does it work?
- Who makes Leukeran, and where is it made?
- How is Rituxan Hycela administered?
- What is the success rate of Breyanzi?
- How does Venclexta work?
- How long does it take for Jaypirca to work?
- How to apply for and use the Imbruvica copay card?
- What type of drug is Copiktra?
Drug information
- Truxima Information for Consumers
- Truxima prescribing info & package insert (for Health Professionals)
- Side Effects of Truxima (detailed)
- Truxima user reviews (4)
Related support groups
- Truxima (5 questions, 4 members)
- Chronic Lymphocytic Leukemia (CLL) (27 questions, 57 members)
- Non-Hodgkin's Lymphoma (17 questions, 39 members)