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What is TPOXX used to treat?

Medically reviewed by Last updated on Aug 13, 2020.

Official Answer


TPOXX (tecovirimat) is used to treat smallpox disease in adults and children who weigh at least 13 kg (28.6 lbs).

Smallpox is caused by the variola virus and was eradicated in 1980; however, there have been longstanding concerns that smallpox could be used as a bioweapon.

Smallpox was mainly spread by direct contact between people before it was eradicated. Symptoms usually started 10 to 14 days after infection and included fever, exhaustion, headache, rash, pus-filled sores (often leading to scarring), and backache. Complications of smallpox could include encephalitis (inflammation of the brain), corneal (eye) ulcerations and blindness.

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