What is TPOXX used to treat?
Medically reviewed by Drugs.com. Last updated on Aug 13, 2020.
Smallpox is caused by the variola virus and was eradicated in 1980; however, there have been longstanding concerns that smallpox could be used as a bioweapon.
Smallpox was mainly spread by direct contact between people before it was eradicated. Symptoms usually started 10 to 14 days after infection and included fever, exhaustion, headache, rash, pus-filled sores (often leading to scarring), and backache. Complications of smallpox could include encephalitis (inflammation of the brain), corneal (eye) ulcerations and blindness.