Stelara and the Covid Vaccine: What should I know?

Stelara (ustekinumab) is an immunosuppressant, meaning it weakens the immune system and may increase the risk of infections, including COVID-19. Additionally, it can reduce the body's response to vaccines, potentially lowering their effectiveness. While there is limited data on how Stelara specifically affects the COVID-19 vaccine, all non-live vaccines, including COVID-19 vaccines, are generally considered safe for Stelara patients.

Should You Get the COVID-19 Vaccine While Taking Stelara?

Patients taking Stelara should talk to their doctor about COVID-19 vaccination. Since Stelara suppresses the immune system, those taking Stelara are considered immunocompromised. The COVID-19 vaccine can help those with weak immune systems by preventing severe illness. The CDC recommends:

Never received a COVID-19 vaccine

• Initial series of an mRNA COVID-19 vaccine (Pfizer or Moderna) from the same brand, followed by 1 dose from any brand 6 months later (minimum time is 2 months apart)

Already completed initial COVID-19 vaccine series

• Get 2 doses of a COVID-19 vaccine from any brand (Moderna, Pfizer-BioNTech, or Novavax), spaced 6 months apart (minimum time is 2 months apart)

Vaccine recommendations may vary based on age and individual health factors. Your healthcare provider may recommend additional doses, at least 2 months after your last dose.

For more details on vaccine timing and schedules, refer to the CDC's guidelines for immunocompromised individuals. Always consult your healthcare provider for personalized medical advice.