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How does Noctiva work?

Medically reviewed by Last updated on Jun 25, 2019.

Official Answer


Noctiva (desmopressin acetate) is a nasal spray for adults who wake up at least two times per night to urinate due to a condition known as nocturnal polyuria (overproduction of urine during the night).

Noctiva works by increasing the absorption of water through the kidneys, which lowers the amount of urine that is produced. In March 2017, Noctiva was the first FDA-approved treatment for nocturnal polyuria.

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