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How often can you take DayQuil? Safe dosage guide

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on Sep 25, 2025.

Official Answer by Drugs.com

You can take DayQuil every 4 hours, but should not exceed 4 doses in 24 hours; always follow the package instructions and consult your healthcare provider if you have questions or underlying health conditions. Taking more than the recommended amount can cause serious side effects.

What Is DayQuil?

DayQuil is an over-the-counter line of medicines designed to relieve common cold and flu symptoms during daytime hours without causing drowsiness. It helps ease body aches, cough, and nasal congestion, making it easier to manage daily activities when sick. The main active ingredients include:

Keep in mind that ingredients in different DayQuil products can vary. For example, some DayQuil products include guaifenesin to help thin mucus and relieve congestion.

DayQuil Dosage Instructions

DayQuil comes in different formulations, including capsules and liquids. Make sure to read the instructions on your specific product for your age group carefully. Below is a list of common DayQuil products found over the counter and their usual dosages.

DayQuil Cold & Flu

Each DayQuil Cold and Flu capsule or 15 mL of the liquid contains:

DayQuil should not be used by children under 12 unless directed by a healthcare provider or using a pediatric-specific formulation. For example, the capsules are only meant for children 12 years and older. The liquid version can be taken by children ages 6 to 12 years old.

Always measure liquid versions with the provided dosing cup or a medicine syringe to ensure accuracy.

DayQuil Severe Cold & Flu

Each DayQuil Severe Cold and Flu capsule or 15 mL of the liquid contains:

Similar to DayQuil Cold & Flu, children ages 6 years and older may use the liquid and people 12 years and older may use the capsules.

There are other DayQuil formulations found on pharmacy shelves, such as DayQuil High Blood Pressure Cold & Flu which does not contain phenylephrine. Another product available is DayQuil Kids Cold & Cough, which does not contain acetaminophen. Talk to your pharmacist to find the best treatment option for your or your child’s cold or flu symptoms.

Risks of Taking Too Much

Taking more than the recommended dose can lead to dangerous health consequences:

Related questions

Special Considerations

Certain individuals should consult a healthcare provider before taking DayQuil. The following groups are at greater risk for side effects or drug interactions:

Drug Interactions to Watch For

Some medications and substances can interact dangerously with DayQuil’s active ingredients, increasing the risk of serious side effects or overdose. It’s important to be aware of these potential interactions to use DayQuil safely.

When to Call a Doctor

Consult a healthcare provider if:

This is not all the information you need to know about DayQuil for safe and effective use and does not take the place of your doctor’s directions. Review the full product instructions and discuss this information and any questions you have with your doctor or other health care provider.

References
  1. A.D.A.M., Inc. (2023, November 2). Dextromethorphan overdose. MedlinePlus. Accessed on September 25, 2025 at https://medlineplus.gov/ency/article/002628.htm
  2. Parra, D., Beckey, N. P., & Stevens, G. R. (2007). The effect of acetaminophen on the international normalized ratio in patients stabilized on warfarin therapy. Pharmacotherapy, 27(5), 675–683. https://doi.org/10.1592/phco.27.5.675
  3. U.S. Food and Drug Administration. (2024, November 7). Should you give kids medicine for coughs and colds? U.S. Food and Drug Administration. Accessed on September 25, 2025 at https://www.fda.gov/consumers/consumer-updates/should-you-give-kids-medicine-coughs-and-colds
  4. Vicks. (n.d.). Vicks DayQuil FAQ. Accessed on September 25, 2025 at https://vicks.com/en-us/safety-and-faqs/faqs/vicks-dayquil-faq
  5. Vicks DayQuil Cold and Flu capsules  [package insert]. Updated August 2025. The Procter & Gamble Manufacturing Company. Accessed on September 25, 2025 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=efb982d4-93d0-815f-e053-2995a90a82dd
  6. Vicks DayQuil Cold and Flu liquid [package insert]. Updated October 2024. The Procter & Gamble Manufacturing Company. Accessed on September 25, 2025 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fc9a43d8-0359-9def-e053-6294a90a7e91
  7. Vicks DayQuil Severe Cold and Flu capsules. Updated August 2025. The Procter & Gamble Manufacturing Company. Accessed on September 25, 2025 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6f013cc1-7885-5025-e053-2a91aa0afe11
  8. Vicks DayQuil Severe Cold and Flu liquid. Updated June 2024. The Procter & Gamble Manufacturing Company. Accessed on September 25, 2025 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5bbe271e-0344-4926-991c-3115756b908e

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