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In the US, Rilpivirine (rilpivirine systemic) is a member of the drug class NNRTIs and is used to treat HIV Infection.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Antivirals for systemic use - Antiviral agent

Non-nucleoside reverse transcriptase inhibitor (NNRTI)

Chemical Name

4-{[4-({4-[(1E)-2-Cyanoetenyl]-2,6-dimetylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile (WHO)

Foreign Names

  • Rilpivirinum (Latin)
  • Rilpivirin (German)
  • Rilpivirine (French)
  • Rilpivirina (Spanish)

Generic Names

  • Rilpivirine (OS: USAN, BAN)
  • R 278474 (IS)
  • TMC-278 (IS)
  • UNII-FI96A8X663 (IS)
  • Rilpivirine Hydrochloride (OS: USAN, JAN, BANM)
  • TMC278 hydrochloride (IS)
  • UNII-212WAX8KDD (IS)

Brand Names

  • Complera [+ Emtricitabine, + Tenofovir]
    Gador, Argentina
  • Edurant
    Janssen-Cilag, Lithuania; Janssen-Cilag, Latvia; Janssen-Cilag, Poland; Janssen-Cilag International, Cyprus; Johnson & Johnson, Croatia (Hrvatska); Johnson & Johnson, Turkey
  • Edurant 25mg
    Abacus, Austria; Janssen-Cilag International, Austria
  • Eviplera [+ Emtricitabine, + Tenofovir]
    Gilead, Lithuania; Gilead, Poland; Gilead, Slovakia; Gilead Sciences, Serbia; Gilead Sciences International, Cyprus; Medicopharmacia, Croatia (Hrvatska)
  • Juluca [+ Dolutegravir]
    ViiV Healthcare, Slovenia
  • Odefsey [+ Emtricitabine, + Tenofovir]
    Gilead, Lithuania; Gilead, Latvia; Gilead Sciences, Slovenia; Gilead Sciences International Ltd, Greece
  • Complera [+ Emtricitabine, + Tenofovir]
    Gilead, United States; Gilead Sciences, Canada
  • Edurant
    Janssen, Canada; Janssen, Denmark; Janssen, Estonia; Janssen, Finland; Janssen, Hong Kong; Janssen, Ireland; Janssen, Malaysia; Janssen, Norway; Janssen, Sweden; Janssen, Singapore; Janssen, Slovenia; Janssen, Slovakia; Janssen Pharma, United States; Janssen Pharmaceutical, Japan; Janssen-Cilag, Australia; Janssen-Cilag, Belgium; Janssen-Cilag, Czech Republic; Janssen-Cilag, Germany; Janssen-Cilag, Spain; Janssen-Cilag, France; Janssen-Cilag, United Kingdom; Janssen-Cilag International, Iceland; Janssen-Cilag International, Romania; Janssen-Cilag International NV, Greece; Janssen-Cilag International NV, Netherlands; J-C Healthcare, Israel
  • Edurant 25mg
    Janssen, Hungary; Janssen-Cilag, Switzerland
  • Edurant-25
    Janssen, Luxembourg
  • Eviplera [+ Emtricitabine, + Tenofovir]
    Gilead, Bosnia & Herzegowina; Gilead, Czech Republic; Gilead, Germany; Gilead, Estonia; Gilead, Spain; Gilead, Finland; Gilead, France; Gilead, Ireland; Gilead, Macedonia; Gilead, Netherlands; Gilead, Norway; Gilead, Portugal; Gilead, Sweden; Gilead Sciences, Australia; Gilead Sciences, Denmark; Gilead Sciences, United Kingdom; Gilead Sciences Belgium, Belgium; Gilead Sciences International, Iceland; Gilead Sciences International Ltd, Greece; J-C Healthcare, Israel
  • Eviplera 200mg/25mg/245mg [+ Emtricitabine, + Tenofovir]
    Abacus, Austria; Eurim-Pharm, Austria; Gilead, Switzerland; Gilead, Luxembourg; Gilead Sciences International, Austria; Haemato Pharm, Austria
  • Juluca [+ Dolutegravir]
    ViiV Healthcare, Australia
  • Odefsey [+ Emtricitabine, + Tenofovir]
    Gilead, Czech Republic; Gilead, Germany; Gilead, Estonia; Gilead, Finland; Gilead, Ireland; Gilead, Luxembourg; Gilead, Norway; Gilead, Sweden; Gilead, United States; Gilead Sciences, Australia; Gilead Sciences, Canada; Gilead Sciences, Denmark; Gilead Sciences, United Kingdom; Gilead Sciences, Romania; Gilead Sciences Belgium, Belgium; Gilead Sciences International, Iceland; Gilead Sciences Ireland UC, Netherlands
  • Odefsey 200 mg/25 mg/25 mg [+ Emtricitabine, + Tenofovir]
    Gilead Sciences International, Austria
  • Odefsey 200/25/25mg [+ Tenofovir, + Emtricitabine]
    Gilead, Switzerland


BANBritish Approved Name
BANMBritish Approved Name (Modified)
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.