Skip to Content


In the US, Rilpivirine (rilpivirine systemic) is a member of the drug class NNRTIs and is used to treat HIV Infection.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Antiviral agent

Non-nucleoside reverse transcriptase inhibitor (NNRTI)

Chemical Name

4-{[4-({4-[(1E)-2-Cyanoetenyl]-2,6-dimetylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile (WHO)

Foreign Names

  • Rilpivirinum (Latin)
  • Rilpivirin (German)
  • Rilpivirine (French)
  • Rilpivirina (Spanish)

Generic Names

  • Rilpivirine (OS: USAN, BAN)
  • R 278474 (IS)
  • TMC-278 (IS)
  • UNII-FI96A8X663 (IS)
  • Rilpivirine Hydrochloride (OS: USAN, JAN, BANM)
  • TMC278 hydrochloride (IS)
  • UNII-212WAX8KDD (IS)

Brand Names

  • Edurant
    Janssen, Slovakia; Janssen-Cilag, Italy; Janssen-Cilag, Lithuania; Janssen-Cilag, Poland; Janssen-Cilag International, Cyprus; Janssen-Cilag Pharma, Austria; Johnson & Johnson, Croatia (Hrvatska)
  • Eviplera (Rilpivirine and Emtricitabine, + Tenofovir)
    Gilead, Poland; Gilead, Slovakia; Gilead Sciences, Italy; Medicopharmacia, Croatia (Hrvatska)
  • Complera (Rilpivirine and Emtricitabine, + Tenofovir)
    Gilead, Canada; Gilead, United States
  • Edurant
    Janssen, Canada; Janssen, Finland; Janssen, Hong Kong; Janssen, Hungary; Janssen, Ireland; Janssen, Iceland; Janssen, Malaysia; Janssen, Norway; Janssen, Romania; Janssen, Sweden; Janssen, Singapore; Janssen, Slovenia; Janssen, Thailand; Janssen Pharma, United States; Janssen Pharmaceutical, Japan; Janssen-Cilag, Belgium; Janssen-Cilag, Switzerland; Janssen-Cilag, Germany; Janssen-Cilag, Denmark; Janssen-Cilag, France; Janssen-Cilag, United Kingdom; Janssen-Cilag, Israel
  • Eviplera (Rilpivirine and Emtricitabine, + Tenofovir)
    Gilead, Australia; Gilead, Belgium; Gilead, Switzerland; Gilead, Germany; Gilead, Denmark; Gilead, Spain; Gilead, Finland; Gilead, France; Gilead, Ireland; Gilead, Iceland; Gilead, Norway; Gilead, Sweden; Gilead, Slovenia; Gilead Sciences, United Kingdom; Gilead Sciences International, Austria; Haemato Pharm, Austria
  • Odefsey (Rilpivirine and Emtricitabine, + Tenofovir)
    Gilead, United States


BANBritish Approved Name
BANMBritish Approved Name (Modified)
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.