Drug Interaction Report

Before receiving DAPTOmycin, tell your doctor if you are taking pravastatin. Both of these medications can cause injury to the muscles, and the risk may be increased when they are used together. If your doctor does prescribe DAPTOmycin, you may need to stop taking pravastatin temporarily while you are being treated with DAPTOmycin, and you may need regular blood tests to monitor for possible muscle damage. Let your doctor know immediately if you have unexplained muscle pain, tenderness, or weakness while taking the medications, especially if these symptoms are accompanied by fever or dark colored urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Pravastatin may cause liver problems and using it with substantial quantities of ethanol (alcohol) may increase that risk. You should limit the use of alcohol while being treated with these medications. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.