Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- calcium saccharate
- estramustine
Interactions between your drugs
estramustine calcium saccharate
Applies to: estramustine, calcium saccharate
ADJUST DOSING INTERVAL: Oral calcium containing products may significantly decrease serum concentrations of estramustine. The mechanism of the interaction is not known.
MANAGEMENT: Estramustine should be taken at least 1 hour before or 2 hours after meals, milk, or calcium containing products.
References (1)
- (2001) "Product Information. Emcyt (estramustine)." Pharmacia and Upjohn
Drug and food interactions
estramustine food
Applies to: estramustine
ADJUST DOSING INTERVAL: Food and milk may significantly decrease serum concentrations of estramustine. The mechanism of the interaction is not known.
MANAGEMENT: It is recommended that estramustine be taken at least 1 hour before or 2 hours after meals, and that it not be coadministered with milk, or calcium containing products.
References (1)
- (2001) "Product Information. Emcyt (estramustine)." Pharmacia and Upjohn
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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