Drug Interaction Report

Celecoxib may increase the blood levels and effects of traMADol. If your doctor does prescribe these medications together, you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or if your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Narcotics and medications that are used to treat insomnia or anxiety may increase the risk and/or severity of nervous system and psychiatric side effects that have been associated with the use of ropeginterferon alfa-2b. These adverse reactions may occur with or without a history of psychiatric illness and may include mental health problems and behaviors such as depression, suicidal thoughts and tendencies, irritability, restlessness, agitation, aggression, confusion, and bipolar disorder. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. You should stop using ropeginterferon alfa-2b immediately and seek medical attention if you experience mental health symptoms or any unusual changes in mood or behavior. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Alcohol can increase the nervous system side effects of traMADol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traMADol. Do not use more than the recommended dose of traMADol, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.