Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- bosentan
- Viekira XR (dasabuvir / ombitasvir / paritaprevir / ritonavir)
Interactions between your drugs
ritonavir bosentan
Applies to: Viekira XR (dasabuvir / ombitasvir / paritaprevir / ritonavir), bosentan
Talk to your doctor before using bosentan together with ritonavir. Combining these medications may significantly increase the blood levels of bosentan, potentially increasing the risk of side effects. You may need a dose adjustment if you have been receiving bosentan and are starting treatment with ritonavir, or vice versa. In addition, you may need more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
ritonavir food
Applies to: Viekira XR (dasabuvir / ombitasvir / paritaprevir / ritonavir)
Ritonavir should be taken with food to lessen gastrointestinal side effects. It is important that you take this medication exactly as prescribed by your doctor. Do not change your treatment or stop treatment without first talking to your doctor.
paritaprevir food
Applies to: Viekira XR (dasabuvir / ombitasvir / paritaprevir / ritonavir)
Food significantly increases the absorption of paritaprevir. You should take each dose of paritaprevir with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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