Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- cilastatin / imipenem / relebactam
- oxtriphylline
Interactions between your drugs
oxtriphylline imipenem
Applies to: oxtriphylline, cilastatin / imipenem / relebactam
MONITOR: Some case reports suggest an increased risk of seizures when theophylline and imipenem are coadministered. The mechanism is unknown. Patients receiving large doses of either drug and/or with renal dysfunction may be at a higher risk.
MANAGEMENT: Dosing should be individualized and patients should be closely monitored for signs of neurotoxicity (e.g., confusion, seizures, myoclonic activity).
References (1)
- Semel JD, Allen N (1991) "Seizures in patients simultaneously receiving theophylline and imipenem or ciprofloxacin or metronidazole." South Med J, 84, p. 465-8
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Cipro
Cipro (ciprofloxacin) is a fluoroquinolone antibiotic used to treat bacterial infections. Learn ...
Flagyl
Flagyl is used to treat bacterial infections of the vagina, stomach, skin and joints. Learn about ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Rocephin
Rocephin (ceftriaxone) is used to treat bacterial infections, including severe or life-threatening ...
Piperacillin/tazobactam
Piperacillin/tazobactam is used for appendectomy, appendicitis, aspiration pneumonia, bacteremia ...
Ampicillin
Ampicillin is used for bacteremia, bacterial endocarditis prevention, bacterial infection ...
Gentamicin
Gentamicin is used for bacteremia, bacterial endocarditis prevention, bacterial infection, bone ...
Meropenem
Meropenem is used for intraabdominal infection, meningitis, nosocomial pneumonia, skin and ...
Clindamycin
Clindamycin (Cleocin) is used to treat serious infections caused by bacteria. Includes clindamycin ...
Ceftriaxone
Ceftriaxone is used for bacteremia, bacterial endocarditis prevention, bacterial infection, bone ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.