Drug Interaction Report

Ritonavir may increase the blood levels of omaveloxolone. This may increase the risk of side effects such as changes in the amount of cholesterol in the blood and changes in liver and heart function tests. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Omaveloxolone may reduce the blood levels of paritaprevir, which may make the medication less effective in some cases. Contact your doctor if your symptoms worsen or your condition changes. You may need more frequent monitoring or a dose adjustment to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Omaveloxolone may reduce the blood levels of dasabuvir, which may make the medication less effective in some cases. Contact your doctor if your symptoms worsen or your condition changes. You may need more frequent monitoring or a dose adjustment to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ritonavir should be taken with food to lessen gastrointestinal side effects. It is important that you take this medication exactly as prescribed by your doctor. Do not change your treatment or stop treatment without first talking to your doctor.

Food significantly increases the absorption of paritaprevir. You should take each dose of paritaprevir with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication.

Omaveloxolone should be taken on an empty stomach, at least one hour before eating. Do not consume grapefruit, grapefruit juice, or any supplements that contain grapefruit extract during treatment with omaveloxolone unless directed otherwise by your doctor. Grapefruit juice may increase the blood levels of omaveloxolone. This may increase the risk of side effects such as changes in the amount of cholesterol in the blood and changes in liver and heart function tests. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.