Drug Interaction Report

Depending on the dose, pantoprazole may interfere with the absorption of ledipasvir and reduce its effectiveness. Talk to your doctor or pharmacist if you have any questions or concerns. You may need a dose adjustment of pantoprazole to safely use both medications. You should take pantoprazole simultaneously with the dose of ledipasvir on an empty stomach. Contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.