Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- siltuximab
- Solfoton (phenobarbital)
Interactions between your drugs
PHENobarbital siltuximab
Applies to: Solfoton (phenobarbital), siltuximab
Siltuximab may decrease the blood levels and effects of PHENobarbital. You may need a dose adjustment if you have been receiving PHENobarbital and are starting treatment with siltuximab. Likewise, if you have been receiving both medications, the dose of PHENobarbital may need to be adjusted when siltuximab is discontinued. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
PHENobarbital food
Applies to: Solfoton (phenobarbital)
Ask your doctor before using PHENobarbital together with ethanol (alcohol), this can add to dizziness, drowsiness and other side effects of PHENobarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with PHENobarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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