Drug Interaction Report

Tirzepatide can cause an increase in heart rate and may have additive effects with other medications that can also increase heart rate such as doxylamine. There are times when an elevated heart rate is appropriate, like when you are exercising. However, you should contact your doctor if you notice that your heart rate is high at other times for unknown reasons or if it is occurring frequently. Signs and symptoms of an elevated heart rate may include a sensation of a racing or pounding heartbeat, chest pain, shortness of breath, or a heart rate greater than 100 beats per minute in an adult. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with doxylamine. Do not use more than the recommended dose of doxylamine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases, this may affect how well and/or how fast those medications work, or it may make no difference. Talk to a healthcare provider if you have any questions or concerns, and contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.