Drug Interaction Report

Talk to your doctor before using boceprevir together with vemurafenib. Combining these medications may decrease the blood levels of boceprevir, which may reduce its effectiveness in treating your condition. At the same time, boceprevir may cause the blood levels of vemurafenib to rise. This may increase the risk of an irregular heart rhythm that may be serious, as well as other side effects of vemurafenib. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food significantly increases the absorption of boceprevir. You should take each dose of boceprevir with a meal or light snack. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication.