Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- ipilimumab
- Xarelto (rivaroxaban)
Interactions between your drugs
rivaroxaban ipilimumab
Applies to: Xarelto (rivaroxaban), ipilimumab
MONITOR CLOSELY: The concomitant use of ipilimumab and anticoagulants may increase the risk of gastrointestinal hemorrhage. Both drugs have been individually associated with this adverse reaction.
MANAGEMENT: If anticoagulant treatment is required, caution and close monitoring for gastrointestinal bleeding is advisable.
References (2)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- EMEA. European Medicines Agency (2007) EPARs. European Union Public Assessment Reports. http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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