Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Aceso Ag (silver topical)
- collagenase topical
Interactions between your drugs
collagenase topical silver topical
Applies to: collagenase topical, Aceso Ag (silver topical)
GENERALLY AVOID: The enzymatic activity of collagenase may be adversely affected by heavy metal ions such as mercury and silver, which are found in some antiseptics. The mechanism of interaction has not been described.
MANAGEMENT: Topical preparations containing heavy metals such as silver and mercury should not be used on wounds treated with collagenase. When it is suspected such products have been used, the site should be carefully cleansed by repeated washings with normal saline before application of collagenase.
References (1)
- (2002) "Product Information. Santyl (collagenase topical)." Knoll Pharmaceutical Company
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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