Drug Interaction Report

Antiviral flu medications like baloxavir marboxil may interfere with the immune response to influenza virus vaccine, H1N1, live. Individuals who have been treated with antiviral flu medications should generally not be vaccinated with influenza virus vaccine, H1N1, live until 24 to 48 hours after stopping treatment. The immunizing doctor should be informed of recent therapy with baloxavir marboxil so that appropriate measures and/or precautions can be taken. Similarly, individuals who have been vaccinated with influenza virus vaccine, H1N1, live must generally wait two weeks before using antiviral flu medications unless otherwise directed by their doctor. If vaccination was given shortly before or during treatment with an antiviral flu medication, a revaccination may be necessary at some point. It is important to tell the doctor about all other medications being used, including vitamins and herbs. Do not stop using any medications without first talking to the doctor.

Baloxavir marboxil may be taken with or without food. However, it should not be taken with dairy products, calcium-fortified beverages, or laxatives, antacids or oral supplements that contain minerals like aluminum, calcium, iron, magnesium, selenium, and zinc. Doing so may interfere with the absorption of baloxavir marboxil and reduce its effectiveness. Talk to your doctor or pharmacist if you have questions on how to take baloxavir marboxil or other medications you are prescribed.