Drug Interaction Report

Vosoritide may cause transitory decreases in blood pressure and may have additive effects when used together with tamsulosin. You may be more likely to experience side effects such as dizziness, weakness, headache, nausea, flushing or fainting. You may need frequent monitoring of your blood pressure to safely use both medications. To reduce the risk of low blood pressure and its associated symptoms, you should have adequate food intake before vosoritide administration and should drink approximately 8 to 10 ounces of liquids within the hour prior to vosoritide injection. Avoid driving or operating hazardous machinery until you know how these medications affect you and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food may affect the intestinal absorption of tamsulosin. You should take tamsulosin approximately one-half hour following the same meal each day to ensure steady absorption and blood levels of the drug.

Vosoritide may cause transient decreases in blood pressure. To reduce the risk of low blood pressure and its associated symptoms, you should have adequate food intake before vosoritide administration and should drink approximately 8 to 10 ounces of liquids within the hour prior to vosoritide injection. Tell your doctor if you experience fatigue, nausea, dizziness, or lightheadedness after vosoritide injection. Avoid driving or operating hazardous machinery until you know how this medication affects you and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.