Drug Interaction Report

Pentamidine can affect kidney function and may increase the blood levels and effects of telbivudine when used together. You may be more likely to develop serious side effects of telbivudine including liver, muscle, and nerve problems. Contact your doctor if you develop skin rash or itching; loss of appetite; abdominal pain; nausea; vomiting; dark colored urine; yellowing of the skin or eyes; unexplained muscle aches, pain, tenderness, or weakness; difficulty walking; or numbness, burning or tingling in your hands and feet. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you experience extreme tiredness or weakness, dizziness, lightheadedness, muscle pain, difficulty breathing, stomach pain, nausea, vomiting, and/or a fast or irregular heart beat, as these may be signs and symptoms of a serious medical condition known as lactic acidosis that can sometimes occur during treatment with medications like telbivudine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.