Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- aminoglutethimide
- Triamonide 40 (triamcinolone)
Interactions between your drugs
aminoglutethimide triamcinolone
Applies to: aminoglutethimide, Triamonide 40 (triamcinolone)
MONITOR: Coadministration with aminoglutethimide may decrease the plasma concentrations of corticosteroids. The proposed mechanism is induction of CYP450 3A4-mediated metabolism by aminoglutethimide.
MANAGEMENT: Patients should be monitored for altered corticosteroid efficacy following the initiation and discontinuation of aminoglutethimide, and the dosage adjusted accordingly to achieve desired clinical effect. If glucocorticoid replacement is necessary, hydrocortisone may be a suitable agent because it does not appear to interact.
References (2)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- Cerner Multum, Inc. "Australian Product Information."
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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