Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- magnesium chloride
- rocuronium
Interactions between your drugs
rocuronium magnesium chloride
Applies to: rocuronium, magnesium chloride
MONITOR: Magnesium salts may enhance the effects of nondepolarizing neuromuscular blocking agents. One study showed a 25% increase in vecuronium potency after intravenous administration of 40 mg/kg of magnesium sulfate.
MANAGEMENT: Patients should be closely monitored for excessive or prolonged neuromuscular blockade and ventilatory support should be immediately available.
References (2)
- (2001) "Product Information. Norcuron (vecuronium)." Organon
- Fuchs-Buder T, Wilder-Smith OH, Borgeat A, Tassonyi E (1995) "Interaction of magnesium sulphate with vecuronium-induced neuromuscular block." Br J Anaesth, 74, p. 405-9
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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