Drug Interaction Report

Using bexarotene together with gemfibrozil is generally not recommended. Combining these medications may significantly increase the blood levels of bexarotene. You may be more likely to experience serious side effects such as elevated cholesterol and triglyceride levels, underactive thyroid (hypothyroidism), liver function abnormalities, low blood cell counts, and inflammation of the pancreas (pancreatitis). Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food helps with the absorption of bexarotene from the gastrointestinal tract into the blood stream. You should take each dose the same time everyday with a meal. Avoid consuming large amounts of grapefruit or grapefruit juice during treatment, since doing so may increase the blood levels of bexarotene. Talk to your doctor or pharmacist if you have any questions or concerns about your medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.