FAQs about the COVID-19 Vaccines
Many people have questions about the COVID-19 vaccines. Here are some answers to these questions based on the current research and advice from the U.S. Centers for Disease Control & Prevention (CDC).
Should I get a COVID-19 vaccine?
The CDC's Advisory Committee on Immunization Practices currently recommends COVID-19 vaccination for all eligible people. The COVID-19 vaccines currently available in the U.S. have been shown to be safe and effective at preventing COVID-19. Information from clinical studies show that vaccination provides protection from infection from the virus or can prevent more serious disease, if infected. If you have had COVID-19, it is still unknown how long and to what extent you are protected after recovering from COVID-19, and it is possible to be infected with COVID-19 again. So even if you had COVID-19 you should still get vaccinated.
Who should not receive a COVID-19 vaccine?
Individuals with a history of these reactions should not receive a COVID-19 vaccine:
- Severe allergic reaction (anaphylaxis) after a previous COVID-19 vaccine dose
- Any immediate allergic reaction after a previous COVID-19 vaccine dose
- Severe allergic reaction (anaphylaxis) to an ingredient in the COVID-19 vaccine
- Known (diagnosed) allergy to an ingredient in the COVID-19 vaccine.
Individuals with these conditions may receive a COVID-19 vaccine, but should contact their health care provider for more information:
- Immunocompromised (problems with your immune system)
- Received monoclonal antibody therapy for COVID-19
- Received convalescent plasma therapy for COVID-19.
How long does it take for protection from the vaccine to kick in?
Protection from the vaccine is considered fully developed two weeks after your final COVID-19 shot (two weeks after the second dose of a 2-dose vaccine and 2 weeks after receiving a single-dose vaccine).
What can I do once I am fully vaccinated?
Current CDC recommendations state that fully vaccinated people can:
- Resume activities without wearing a mask or staying 6 feet apart, except when required by federal, state, local, tribal, or territorial laws, rules, and regulations, including local business and workplace guidance.
- Travelers (vaccinated and unvaccinated) are NOT required to wear a mask on all planes, buses, trains, and other forms of public transportation traveling into, within, or out of the U.S., but may chose to do so
- Travel in the U.S. without testing before or after
- Travel in the U.S. without quarantining afterward
- Travel internationally without a pre-travel test (depending on destination)
- Travel internationally without quarantining afterward in the U.S.
Related questions
- Can you take Ibuprofen after the COVID booster vaccine?
- What is a viral infection?
- Preguntas frecuentes sobre las vacunas contra la COVID-19
Are COVID-19 vaccines still being studied?
Researchers have reported that these vaccines are effective to prevent serious illness and death from COVID-19 and also to reduce the spread of the disease. However, more study is needed to know how long the vaccines will protect people from COVID-19 and how well they protect against changes in the virus over time.
Can a child under 12 years old receive a COVID-19 vaccine?
Yes. Children from aged 6 months to 12 years and older can receive either the Moderna or Pfizer-BioNTech COVID-19 vaccines. Boosters are recommended for those aged 5 years and older who are eligible. See the CDC website for more information about COVID-19 Vaccination for Children.
Summary
Even if you have had COVID-19, it is still important to get vaccinated. The vaccine remains recommended for everyone unless you have a history of the specific allergic reactions mentioned above or if your doctor tells you not to be vaccinated. It does take two weeks after your final COVID-19 shot to develop full protection. Recommendations from the CDC may change as experts continue to learn more about COVID-19 from clinical studies and from monitoring disease activity.
See also:
Wegovy
Wegovy (semaglutide) an FDA-approved weekly injection for weight loss and to reduce heart risks ...
Rybelsus
Rybelsus tablets are used to improve blood sugar control in adults with type 2 diabetes, and may ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Zepbound
Zepbound (tirzepatide) is an FDA-approved weekly injection for weight loss and obstructive sleep ...
Trulicity
Trulicity is an injectable diabetes medicine that is used together with diet and exercise to ...
Lantus
Lantus is a long acting form of insulin used to treat type 1 or type 2 diabetes. Learn about side ...
Tresiba
Tresiba (insulin degludec) is used to treat diabetes mellitus. Includes Tresiba side effects ...
Victoza
Victoza helps control blood sugar levels and reduce the risk of serious heart problems in people ...
Levemir
Levemir (insulin detemir) is a long acting insulin used to treat diabetes in adults and children ...
Related medical questions
- Which breathing techniques help with COVID-19?
- How effective is Lagevrio (molnupiravir) for COVID-19?
- Is Omicron worse than Delta?
- COVID-19 vaccines and variants: What you should know
- Should I wear a face mask to protect myself from COVID-19?
- COVID-19: Why is social distancing so important?
- Why do more men die from coronavirus?
- Can ivermectin be used to treat COVID-19?
- Can you take Ibuprofen if you have COVID-19 (coronavirus)?
- What antibiotics kill Covid-19 (coronavirus)?
- COVID-19: What are the Stages and Causes of Death?
- What's the difference between Bacteria and Viruses?
- Does Zinc protect you from Covid-19 or boost your immune system?
- How do I Treat Nasal Congestion with COVID-19?
- Does Losartan block the receptor used by the Coronavirus?
- An Update: Is hydroxychloroquine effective for COVID-19?
- Where can I buy an at-home test kit for COVID-19 (coronavirus)?
- Can you take Paxlovid twice if COVID rebounds?
- Does Paxlovid make you less contagious?
- Does Tamiflu (oseltamivir) work on COVID-19?
- Can vitamin C prevent or treat COVID-19 (coronavirus)?
- Does Mucinex help with Covid?
- Should I take Paxlovid after a Positive COVID-19 Test?
- Can I take NyQuil with COVID or after the COVID vaccine?
- How long does COVID-19 last? and other COVID-19 FAQ
- How effective is Paxlovid for COVID-19?
- What are JAK inhibitors and how do they work?
Related support groups
- Sars-cov-2 (covid-19) Mrna (tozinameran 12y+) Bivalent Booster Vaccine (4 questions, 3 members)
- Sars-cov-2 (covid-19) Mrna-1273 (bivalent Booster) Vaccine (3 questions, 3 members)
- Sars-cov-2 (covid-19) Mrna-1273 (6m-5y Bivalent Booster) Vaccine (2 questions, 3 members)
- Sars-cov-2 (covid-19)mrna-1273(6y+ Bivalent Booster) Vaccine (1 questions, 3 members)
- COVID-19 (103 questions, 90 members)
- Vaccination and Prophlaxis (13 questions, 4 members)

AHFS® Patient Medication Information is used with permission. ©2025, the American Society of Health-System Pharmacists, Inc. (ASHP). The ASHP Data is a part of the AHFS Drug Information®️; ASHP is not responsible for the accuracy of transpositions from the original context.