Umbralisib and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with umbralisib.
Umbralisib Food
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food enhances the oral bioavailability of umbralisib. When a single oral dose of umbralisib was administered with a high-fat, high-calorie meal (approximately 917 calories; 171 calories from protein, 232 calories from carbohydrate, 502 calories from fat) in healthy subjects, umbralisib peak plasma concentration (Cmax) and systemic exposure (AUC) increased by 115% and 61%, respectively, compared to administration under fasted conditions.
MANAGEMENT: Umbralisib should be administered with food at approximately the same time each day.
References (1)
- "Multum Information Services, Inc. Expert Review Panel"
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Umbralisib drug interactions
There are 196 drug interactions with umbralisib.
Umbralisib disease interactions
There are 4 disease interactions with umbralisib which include:
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- Drug class: multikinase inhibitors
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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