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Kayexalate (sodium polystyrene sulfonate) and Alcohol / Food Interactions

There are 2 alcohol/food/lifestyle interactions with Kayexalate (sodium polystyrene sulfonate) which include:


sodium polystyrene sulfonate ↔ multivitamins with minerals

Moderate Drug Interaction

Sodium polystyrene sulfonate can bind to calcium, iron, magnesium, and other minerals in the gastrointestinal tract. This may inactivate both sodium polystyrene sulfonate and the mineral it binds to and reduce the effectiveness of both medications. To avoid or minimize the interaction, the dosing times of sodium polystyrene sulfonate and multivitamin with minerals should be separated by several hours. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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sodium polystyrene sulfonate ↔ food

Moderate Food Interaction

While taking sodium polystyrene sulfonate, you should avoid moderately high or high potassium dietary intake. This can cause high levels of potassium in your blood. Do not use salt substitutes, potassium supplements, orange juice or other foods with a high potassium content while taking sodium polystyrene sulfonate, unless your doctor has told you to.

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Kayexalate (sodium polystyrene sulfonate) drug Interactions

There are 164 drug interactions with Kayexalate (sodium polystyrene sulfonate)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

Do not stop taking any medications without consulting your healthcare provider.

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