Sildenafil and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with sildenafil.
Alcohol (Ethanol) Sildenafil
Moderate Drug Interaction
Sildenafil can lower blood pressure, and combining it with ethanol (alcohol) may further increase this effect. You may be more likely to experience symptoms such as dizziness, lightheadedness, fainting, flushing, headache, and heart palpitations. You should avoid or limit the use of alcohol to not more than 4 alcohol-containing drinks during a small period of time while being treated with sildenafil, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Sildenafil Food
Moderate Food Interaction
If you are receiving therapy with sildenafil you should avoid the regular consumption of large amounts of grapefruits and grapefruit juice. Grapefruit can raise the levels of sildenafil in your body and delay the time it takes for the medication to work. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Sildenafil drug interactions
There are 361 drug interactions with sildenafil.
Sildenafil disease interactions
There are 10 disease interactions with sildenafil which include:
- cardiovascular disease
- priapism
- alcoholism
- hearing loss
- liver disease
- seizure disorders
- sickle cell disease
- bleeding disorders
- renal dysfunction
- visual disorders
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- During pregnancy
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- Drug class: agents for pulmonary hypertension
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.