Copegus and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Copegus (ribavirin).
Ribavirin Food
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food enhances the oral absorption and bioavailability of ribavirin. Administration of a single oral dose of ribavirin following a high-fat meal delayed absorption (Tmax was doubled) but increased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by up to 70% compared to administration in the fasting state.
MANAGEMENT: To ensure maximal oral absorption, ribavirin should be administered with or immediately after a meal.
References (2)
- (2003) "Product Information. Copegus (ribavirin)." Roche Laboratories
- (2004) "Product Information. Rebetol (ribavirin)." Schering-Plough Corporation
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Copegus drug interactions
There are 18 drug interactions with Copegus (ribavirin).
Copegus disease interactions
There are 4 disease interactions with Copegus (ribavirin) which include:
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More about Copegus (ribavirin)
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- During pregnancy
- Generic availability
- Drug class: inhaled anti-infectives
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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