8-MOP and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with 8-MOP (methoxsalen).
Methoxsalen Food/Lifestyle
Moderate Food Interaction
GENERALLY AVOID: The ingestion of foods containing photosensitizing components (e.g., limes, figs, parsley, parsnips, rue (Ruta graveolens), mustard, carrots and celery) may increase the risk of photosensitivity and severe burning during methoxsalen therapy. Two cases of photosensitivity involving rue and a soup containing celery, parsley, and parsnip have been reported in PUVA patients.
MANAGEMENT: Patients who are undergoing PUVA treatment and taking methoxsalen should be advised to avoid eating large quantities of these foods.
References (1)
- the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT), Royal Australian College of General Practicioners (RACGP), the Pharmaceutical Society of Australia (PSA) (2007) Australian Medicines Handbook. https://www.amh.net.au/
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8-MOP drug interactions
There are 147 drug interactions with 8-MOP (methoxsalen).
8-MOP disease interactions
There are 7 disease interactions with 8-MOP (methoxsalen) which include:
- aphakia
- photosensitivity states
- skin cancer
- cardiac disease
- liver disease
- previous x-ray therapy
- sunburn
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More about 8-MOP (methoxsalen)
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- During pregnancy
- Drug class: psoralens
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
