Megace and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Megace (megestrol).
Megestrol High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
estrogens/progestogens - fluid retention
Estrogens and progestogens may cause fluid retention, particularly when given in high dosages or for prolonged periods. Therapy with these agents should be administered cautiously in patients who have preexisting problems with excess fluid. In addition, patients with conditions that may be adversely affected by fluid accumulation, such as asthma, epilepsy, migraine, and cardiovascular or renal dysfunction, should be observed for exacerbation of their condition during estrogen and/or progestogen therapy.
References (27)
- Leiman G (1972) "Depo-medroxyprogesterone acetate as a contraceptive agent: its effect on weight and blood pressure." Am J Obstet Gynecol, 114, p. 97-102
- (2001) "Product Information. Depo-Provera (medroxyprogesterone)." Pharmacia and Upjohn
- (2001) "Product Information. Provera (medroxyprogesterone)." Pharmacia and Upjohn
- (2001) "Product Information. Premarin (conjugated estrogens)." Wyeth-Ayerst Laboratories
- (2001) "Product Information. Climara (estradiol)." Berlex Laboratories
- (2001) "Product Information. Estrace (estradiol)." Warner Chilcott Laboratories
- (2001) "Product Information. Estraderm (estradiol)." Ciba-Geigy Pharmaceuticals
- (2001) "Product Information. Vivelle (estradiol)." Ciba-Geigy Pharmaceuticals
- "Product Information. Ortho-Novum 10/11 (ethinyl estradiol-norethindrone)." Ortho McNeil Pharmaceutical
- (2001) "Product Information. Ortho-Cept (desogestrel-ethinyl estradiol)." Ortho McNeil Pharmaceutical
- "Product Information. Demulen 1/50 (ethinyl estradiol-ethynodiol)." Searle
- (2001) "Product Information. Triphasil (ethinyl estradiol-levonorgestrel)." Wyeth-Ayerst Laboratories
- (2001) "Product Information. Ortho-Cyclen (ethinyl estradiol-norgestimate)." Ortho McNeil Pharmaceutical
- (2001) "Product Information. Lo/Ovral (ethinyl estradiol-norgestrel)." Wyeth-Ayerst Laboratories
- "Product Information. Ortho-Novum 1/50 (mestranol-norethindrone)." Ortho McNeil Pharmaceutical
- (2001) "Product Information. Emcyt (estramustine)." Pharmacia and Upjohn
- (2001) "Product Information. Megace (megestrol)." Bristol-Myers Squibb
- (2001) "Product Information. Ortho-Est (estropipate)." Ortho McNeil Pharmaceutical
- "Product Information. Ortho Dienestrol (dienestrol topical)." Ortho McNeil Pharmaceutical
- (2001) "Product Information. Ogen (estropipate topical)." Pharmacia and Upjohn
- "Product Information. Estinyl (ethinyl estradiol)." Schering Corporation
- (2001) "Product Information. Estratab (esterified estrogens)." Solvay Pharmaceuticals Inc
- (2001) "Product Information. Norplant System (levonorgestrel)." Wyeth-Ayerst Laboratories
- (2001) "Product Information. Micronor (norethindrone)." Ortho McNeil Pharmaceutical
- (2001) "Product Information. Ovrette (norgestrel)." Wyeth-Ayerst Laboratories
- (2001) "Product Information. Prometrium (progesterone)." Virtus Pharmaceuticals LLC
- (2006) "Product Information. Implanon (etonogestrel)." Organon Pharmaceuticals
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Megace drug interactions
There are 179 drug interactions with Megace (megestrol).
Megace disease interactions
There are 5 disease interactions with Megace (megestrol) which include:
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More about Megace (megestrol)
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- Dosage information
- During pregnancy
- Drug class: hormones/antineoplastics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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