OptiMARK and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with OptiMARK (gadoversetamide).
Gadoversetamide High Blood Pressure (Hypertension)
Major Potential Hazard, Moderate plausibility
GBCAs - renal impairment
Gadolinium- based contrast agents (GBCAs) such as gadopentetate dimeglumine, gadoteridol and gadodiamide are contraindicated in patients with chronic, severe kidney disease (glomerular filtration rate, GFR < 30 mL/min), or acute kidney injury. GBCAs increase the risk for nephrogenic systemic fibrosis (NSF) among patients with impaired elimination of the drugs. Their use should be avoided in these patients unless the diagnostic information is essential and not available with non- contrasted MRI or other modalities. NSF may result in fatal or debilitating fibrosis affecting the skin, muscle and internal organs. Caution is advised in patients at risk for chronically reduced renal function (age >60 years, hypertension or diabetes). Always estimate the glomerular filtration rate (GFR) through laboratory testing.
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OptiMARK drug interactions
There are 30 drug interactions with OptiMARK (gadoversetamide).
OptiMARK disease interactions
There are 3 disease interactions with OptiMARK (gadoversetamide) which include:
More about OptiMARK (gadoversetamide)
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- During pregnancy
- Drug class: magnetic resonance imaging contrast media
- Breastfeeding
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Multihance
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Omniscan
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.