Zenapax (daclizumab) and Alcohol / Food Interactions
There is 1 alcohol/food/lifestyle interaction with Zenapax (daclizumab):
Alcohol (Ethanol) ↔ daclizumab
Moderate Drug Interaction
Consumer information for this interaction is not currently available.
MONITOR: Coadministration of daclizumab with other agents known to induce hepatotoxicity may increase the risk of liver injury. Serious drug-related hepatic injury, including liver failure and autoimmune hepatitis, has been reported across controlled and open-label studies in 1.7% of daclizumab-treated patients and may occur at any time during treatment and up to 5 months after treatment cessation. Fatal cases have occurred. In addition, cases of hepatic injury have occurred in patients taking daclizumab concomitantly with other hepatotoxic drugs; however, the contributory role of these other medicines has not been established.
MANAGEMENT: Caution is advised if daclizumab is used with other potentially hepatotoxic agents, including non-prescription products and herbal supplements. Patients treated with daclizumab should have serum transaminase levels and total bilirubin measured prior to initiation of treatment and monthly during treatment in accordance with the manufacturer's recommendations, and the dosing adjusted or interrupted as necessary. Patients should be advised to seek medical attention if they experience potential signs and symptoms of hepatotoxicity such as fever, rash, itching, anorexia, nausea, vomiting, fatigue, malaise, right upper quadrant pain, dark urine, pale stools, and jaundice.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. Zinbryta (daclizumab)." AbbVie US LLC, North Chicago, IL.
Zenapax (daclizumab) drug Interactions
There are 541 drug interactions with Zenapax (daclizumab)
Zenapax (daclizumab) disease Interactions
There are 5 disease interactions with Zenapax (daclizumab) which include:
More about Zenapax (daclizumab)
- Zenapax Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Drug class: interleukin inhibitors
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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