DurAct and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with DurAct (bromfenac).
Bromfenac Food
Moderate Food Interaction
ADJUST DOSE: In-vivo studies have demonstrated that the absorption of bromfenac is greatly reduced if the drug is taken within three and one-half hours following a high fat meal. The concomitant administration of a high fat meal has led to a 75% reduction in peak plasma concentrations and a 60% reduction in total area under the curve. The mechanism has not been described.
MANAGEMENT: An increased dosage of bromfenac (from 25 to 50 mg) may be needed if a high fat meal is consumed. The clinician may want to warn the patient about subtherapeutic analgesic effects if high fat meals are regularly consumed.
References (1)
- "Product Information. DurAct (bromfenac)." Wyeth-Ayerst Laboratories
Switch to consumer interaction data
DurAct drug interactions
There are 370 drug interactions with DurAct (bromfenac).
DurAct disease interactions
There are 2 disease interactions with DurAct (bromfenac) which include:
Report options
More about DurAct (bromfenac)
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
A-G Profen
A-G Profen is used for aseptic necrosis, back pain, chronic myofascial pain, costochondritis ...
Addaprin
Addaprin is used for aseptic necrosis, back pain, chronic myofascial pain, costochondritis, diffuse ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Advil
Advil (ibuprofen) reduces fever, pain and inflammation caused by headaches, toothaches, arthritis ...
Advil Children's
Advil Children's is used for fever, headache, juvenile rheumatoid arthritis, muscle pain, pain ...
Advil Migraine
Advil Migraine is used for headache, juvenile rheumatoid arthritis, pain
Aflaxen
Aflaxen is used for ankylosing spondylitis, aseptic necrosis, back pain, bursitis, chronic ...
Aleve
Aleve is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. Learn ...
Aleve Back and Muscle Pain
Aleve Back and Muscle Pain is used for back pain, muscle pain
Anaprox-DS
Anaprox-DS is used for ankylosing spondylitis, aseptic necrosis, back pain, bursitis, chronic ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.