Selpercatinib Drug Interactions
Currently displaying a list of 629 drugs known to interact with selpercatinib.
- 289 major drug interactions
- 318 moderate drug interactions
- 22 minor drug interactions
Medications known to interact with selpercatinib
Note: Showing generic names only.
A
- abametapir topical
- abarelix
- abemaciclib
- abiraterone
- acalabrutinib
- adagrasib
- adenosine
- ado-trastuzumab emtansine
- afatinib
- albendazole
- albuterol
- alfentanil
- alfuzosin
- aliskiren
- alprazolam
- aluminum carbonate
- aluminum hydroxide
- ambrisentan
- aminoglutethimide
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amprenavir
- anagrelide
- apalutamide
- apixaban
- apomorphine
- aprepitant
- arformoterol
- aripiprazole
- armodafinil
- arsenic trioxide
- artesunate
- asciminib
- asenapine
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atazanavir
- atogepant
- atomoxetine
- atorvastatin
- avacopan
- avanafil
- avapritinib
- avatrombopag
- axitinib
- azithromycin
B
- bedaquiline
- belzutifan
- benzgalantamine
- bepridil
- berotralstat
- betamethasone
- betrixaban
- bexarotene
- bicalutamide
- binimetinib
- bisacodyl
- bitolterol
- black cohosh
- boceprevir
- bosentan
- bosutinib
- brentuximab
- brexpiprazole
- brigatinib
- bromocriptine
- budesonide
- budesonide nasal
- buprenorphine
- buspirone
- butabarbital
- butalbital
C
- cabazitaxel
- cabozantinib
- calaspargase pegol
- calcium carbonate
- cannabidiol
- capivasertib
- carbamazepine
- cariprazine
- casanthranol
- cascara sagrada
- castor oil
- cenobamate
- ceritinib
- cerivastatin
- cevimeline
- chloramphenicol
- chloroquine
- chlorotrianisene
- chlorpromazine
- cilostazol
- cimetidine
- ciprofloxacin
- cisapride
- citalopram
- clarithromycin
- clofarabine
- clofazimine
- clomipramine
- clonazepam
- clorazepate
- clotrimazole
- clozapine
- cobicistat
- cobimetinib
- colchicine
- conivaptan
- conjugated estrogens
- copanlisib
- cortisone
- crizotinib
- cyclosporine
D
- dabigatran
- dabrafenib
- daclatasvir
- daclizumab
- danazol
- daprodustat
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- deflazacort
- degarelix
- delavirdine
- desipramine
- deutetrabenazine
- dexamethasone
- dexlansoprazole
- dienestrol topical
- digoxin
- dihydroergotamine
- dihydroxyaluminum sodium carbonate
- diltiazem
- disopyramide
- docetaxel
- dofetilide
- dolasetron
- dolutegravir
- donepezil
- doravirine
- doxazosin
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- dronedarone
- droperidol
- drospirenone
- dutasteride
- duvelisib
E
- echinacea
- edoxaban
- efavirenz
- elacestrant
- elafibranor
- elagolix
- eletriptan
- eliglustat
- encorafenib
- enfortumab vedotin
- entrectinib
- enzalutamide
- epirubicin
- eplerenone
- erdafitinib
- ergonovine
- ergotamine
- eribulin
- erlotinib
- erythromycin
- escitalopram
- eslicarbazepine
- esomeprazole
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethinyl estradiol
- ethosuximide
- etonogestrel
- etoposide
- etranacogene dezaparvovec
- etrasimod
- etravirine
- everolimus
- ezogabine
F
- famotidine
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fentanyl
- fesoterodine
- fexinidazole
- fexofenadine
- fidanacogene elaparvovec
- fidaxomicin
- finerenone
- fingolimod
- flecainide
- flibanserin
- fluconazole
- fludrocortisone
- fluoxetine
- fluphenazine
- flurazepam
- flutamide
- fluvoxamine
- formoterol
- fosamprenavir
- fosaprepitant
- foscarnet
- fosphenytoin
- fostamatinib
- fostemsavir
G
- galantamine
- ganaxolone
- gatifloxacin
- gefitinib
- gemifloxacin
- gepirone
- gilteritinib
- ginger
- givinostat
- glasdegib
- glycerin
- glycerol phenylbutyrate
- goldenseal
- goserelin
- granisetron
- grepafloxacin
- griseofulvin
- guanfacine
H
- halofantrine
- haloperidol
- halothane
- histrelin
- hydrocodone
- hydrocortisone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyzine
I
- ibrexafungerp
- ibrutinib
- ibutilide
- idarubicin
- idelalisib
- iloperidone
- imatinib
- imipramine
- indacaterol
- indinavir
- infigratinib
- inotuzumab ozogamicin
- interferon beta-1a
- interferon beta-1b
- iptacopan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isoetharine
- isoniazid
- isoproterenol
- isotretinoin
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivermectin
- ivosidenib
- ixabepilone
K
L
- lactitol
- lactulose
- lanreotide
- lansoprazole
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- lenvatinib
- lesinurad
- letermovir
- letrozole
- leuprolide
- levalbuterol
- levobupivacaine
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- lisdexamfetamine
- lithium
- lofexidine
- lomefloxacin
- lomitapide
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- loperamide
- loratadine
- lorlatinib
- lovastatin
- lumateperone
- lurasidone
- lurbinectedin
- lusutrombopag
M
- macimorelin
- macitentan
- magaldrate
- magnesium carbonate
- magnesium citrate
- magnesium hydroxide
- magnesium oxide
- maprotiline
- maraviroc
- mavacamten
- mavorixafor
- medroxyprogesterone
- mefloquine
- megestrol
- mephobarbital
- mesoridazine
- metaproterenol
- metformin
- methadone
- methotrexate
- methotrimeprazine
- methylergonovine
- methylnaltrexone
- methylprednisolone
- methysergide maleate
- metreleptin
- metronidazole
- mibefradil
- miconazole
- midazolam
- midostaurin
- mifepristone
- mineral oil
- mipomersen
- mirabegron
- mirtazapine
- mitapivat
- mitotane
- mitoxantrone
- mobocertinib
- modafinil
- montelukast
- morphine
- moxifloxacin
N
- nafcillin
- naldemedine
- naloxegol
- naltrexone
- naproxen
- nefazodone
- nelfinavir
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nilutamide
- nimodipine
- nintedanib
- niraparib
- nirogacestat
- nisoldipine
- nitisinone
- nizatidine
- norethindrone
- norfloxacin
- norgestrel
- nortriptyline
O
- octreotide
- ofloxacin
- olanzapine
- olaparib
- oliceridine
- olodaterol
- olutasidenib
- omeprazole
- ondansetron
- oritavancin
- osilodrostat
- osimertinib
- oxaliplatin
- oxcarbazepine
- oxybutynin
- oxycodone
- oxytocin
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- paliperidone
- palonosetron
- palovarotene
- panobinostat
- pantoprazole
- papaverine
- pasireotide
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pemigatinib
- pentamidine
- pentobarbital
- perflutren
- perphenazine
- pexidartinib
- phenobarbital
- phenolphthalein
- phenylbutazone
- phenytoin
- pimavanserin
- pimecrolimus topical
- pimozide
- pioglitazone
- pirbuterol
- pirtobrutinib
- pitolisant
- polatuzumab vedotin
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- ponesimod
- posaconazole
- pralsetinib
- praziquantel
- prednisolone
- prednisone
- primaquine
- primidone
- probucol
- procainamide
- prochlorperazine
- progesterone
- progesterone topical
- promazine
- promethazine
- propafenone
- propofol
- propoxyphene
- protriptyline
- prucalopride
Q
R
- rabeprazole
- ranitidine
- ranitidine bismuth citrate
- ranolazine
- red yeast rice
- relugolix
- remdesivir
- repaglinide
- repotrectinib
- resmetirom
- retapamulin topical
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rifaximin
- rilpivirine
- rimegepant
- riociguat
- ripretinib
- risperidone
- ritlecitinib
- ritodrine
- ritonavir
- rivaroxaban
- rivastigmine
- roflumilast topical
- romidepsin
- ropivacaine
- rosiglitazone
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- salmeterol
- saquinavir
- saxagliptin
- secobarbital
- selexipag
- selumetinib
- senna
- sertraline
- sevoflurane
- sibutramine
- sildenafil
- silodosin
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- sodium bicarbonate
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sonidegib
- sorafenib
- sotalol
- sotorasib
- sparfloxacin
- sparsentan
- st. john's wort
- sulfamethoxazole
- sulfinpyrazone
- sunitinib
- suvorexant
- suzetrigine
T
- tacrine
- tacrolimus
- tadalafil
- talazoparib
- tamoxifen
- tamsulosin
- tasimelteon
- tazemetostat
- tebentafusp
- tecovirimat
- telaprevir
- telavancin
- telithromycin
- telotristat
- temsirolimus
- teniposide
- tenofovir alafenamide
- tenofovir disoproxil
- tepotinib
- terbutaline
- terfenadine
- teriflunomide
- testosterone
- testosterone topical
- tetrabenazine
- thalidomide
- thioguanine
- thioridazine
- thiotepa
- tiagabine
- ticagrelor
- tinidazole
- tipranavir
- tizanidine
- tofacitinib
- tolterodine
- tolvaptan
- topotecan
- toremifene
- torsemide
- tovorafenib
- trabectedin
- tramadol
- trazodone
- treosulfan
- treprostinil
- tretinoin
- triamcinolone
- triazolam
- triclabendazole
- trifluoperazine
- triflupromazine
- trimeprazine
- trimipramine
- triptorelin
- trofinetide
- troglitazone
- troleandomycin
- tucatinib
U
V
- vadadustat
- valbenazine
- valdecoxib
- valoctocogene roxaparvovec
- vandetanib
- vardenafil
- vasopressin
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- viloxazine
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vitamin a
- voclosporin
- vonoprazan
- vorasidenib
- voriconazole
- voxelotor
W
Z
Selpercatinib alcohol/food interactions
There are 2 alcohol/food interactions with selpercatinib.
Selpercatinib disease interactions
There are 7 disease interactions with selpercatinib which include:
- bleeding
- hypertension
- ILD/pneumonitis
- liver dysfunction
- tumor lysis syndrome
- Selpercatinib – arrhythmias
- Selpercatinib – renal dysfunction
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More about selpercatinib
- selpercatinib consumer information
- Check interactions
- Compare alternatives
- Reviews (5)
- Side effects
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- During pregnancy
- Drug class: multikinase inhibitors
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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