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Drug interactions between methotrexate and Orencia

Results for the following 2 drugs:
methotrexate
Orencia (abatacept)

Interactions between your drugs

There were no interactions found in our database between methotrexate and Orencia. However, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

methotrexate

A total of 850 drugs (3855 brand and generic names) are known to interact with methotrexate.

Orencia

A total of 112 drugs (342 brand and generic names) are known to interact with Orencia.

Drug and food interactions

Moderate

methotrexate food

Applies to: methotrexate

Caffeine may reduce the effectiveness of methotrexate in the treatment of arthritis. If you are receiving methotrexate for arthritis, you may want to limit your intake of caffeine-containing foods and medications. Check with your doctor or pharmacist if you have concerns or are uncertain what products may contain caffeine.

Switch to professional interaction data

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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