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Drug interactions between methadone and Tylenol

Results for the following 2 drugs:
methadone
Tylenol (acetaminophen)

Interactions between your drugs

There were no interactions found in our database between methadone and Tylenol - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

methadone

A total of 1135 drugs (6188 brand and generic names) are known to interact with methadone.

Tylenol

A total of 177 drugs (1079 brand and generic names) are known to interact with Tylenol.

Drug and food interactions

Moderate

methadone food

Applies to: methadone

Grapefruit juice can increase the blood levels and effects of methadone. If you regularly consume grapefruits or grapefruit juice, you should be monitored for side effects and/or changes in methadone levels. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Orange juice is not expected to interact.

Switch to professional interaction data

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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