Levodopa Interactions
There are 519 drugs known to interact with levodopa, along with 11 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 50 are major, 458 are moderate, and 11 are minor.
- View all 519 medications that may interact with levodopa
- View levodopa alcohol/food interactions (1)
- View levodopa disease interactions (11)
Most frequently checked interactions
View interaction reports for levodopa and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- 5-HTP (5-hydroxytryptophan)
- Acetylsalicylic Acid (aspirin)
- Acetylsalicylic Acid (aspirin)
- Azilect (rasagiline)
- Azilect (rasagiline)
- Crestor (rosuvastatin)
- Crestor (rosuvastatin)
- Ginkgo Biloba (ginkgo)
- Ginkgo Biloba (ginkgo)
- L-Tyrosine (tyrosine)
- L-Tyrosine (tyrosine)
- Paracetamol (acetaminophen)
- Paracetamol (acetaminophen)
- Seroquel (quetiapine)
- Seroquel (quetiapine)
- Sinemet (carbidopa / levodopa)
- Sinemet (carbidopa / levodopa)
- Valproate Sodium (valproic acid)
- Valproate Sodium (valproic acid)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin B6 (pyridoxine)
- Vitamin B6 (pyridoxine)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zoloft (sertraline)
- Zoloft (sertraline)
Levodopa alcohol/food interactions
There is 1 alcohol/food interaction with levodopa.
Levodopa disease interactions
There are 11 disease interactions with levodopa which include:
- cardiac disease
- neuroleptic malignant syndrome
- psychoses/depression
- glaucoma
- liver/renal
- melanoma
- reactive airway disease
- sleep disorders
- hypotension
- psychosis
- GI bleeding
Report options
More about levodopa
- levodopa consumer information
- Compare alternatives
- Reviews (1)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: dopaminergic antiparkinsonism agents
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
