Irinotecan Interactions
There are 448 drugs known to interact with irinotecan, along with 4 disease interactions. Of the total drug interactions, 93 are major, 328 are moderate, and 27 are minor.
- View all 448 medications that may interact with irinotecan
- View irinotecan disease interactions (4)
Most frequently checked interactions
View interaction reports for irinotecan and the medicines listed below.
- Ativan (lorazepam)
- Ativan (lorazepam)
- Avastin (bevacizumab)
- Avastin (bevacizumab)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Compazine (prochlorperazine)
- Compazine (prochlorperazine)
- Creon (pancrelipase)
- Creon (pancrelipase)
- Decadron (dexamethasone)
- Decadron (dexamethasone)
- Dilaudid (hydromorphone)
- Dilaudid (hydromorphone)
- Fentanyl Transdermal System (fentanyl)
- Fentanyl Transdermal System (fentanyl)
- Imodium (loperamide)
- Imodium (loperamide)
- Neulasta (pegfilgrastim)
- Neulasta (pegfilgrastim)
- Paracetamol (acetaminophen)
- Paracetamol (acetaminophen)
- Vectibix (panitumumab)
- Vectibix (panitumumab)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zofran (ondansetron)
- Zofran (ondansetron)
Irinotecan disease interactions
There are 4 disease interactions with irinotecan which include:
More about irinotecan
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- Reviews (3)
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous antineoplastics
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
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Avastin
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Opdivo Qvantig
Opdivo Qvantig is used to treat adults with melanoma, non-small cell lung cancer, renal cell ...
Xeloda
Xeloda is used to treat breast and colorectal cancers. Learn about side effects, interactions and ...
Betaseron
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Extavia
Extavia is used to treat the relapsing forms of multiple sclerosis. Learn about side effects ...
Leucovorin
Leucovorin is used for anemia, megaloblastic, colorectal cancer, folic acid antagonist overdose ...
Nivolumab
Nivolumab is used to treat melanoma, non-small cell lung cancer, malignant pleural mesothelioma ...
Bevacizumab
Bevacizumab injection is a targeted cancer drug used to treat types of non-small cell lung cancer ...
Pembrolizumab
Pembrolizumab (Keytruda) is a monoclonal antibody cancer medicine used to treat
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.