Phenylephrine HD Interactions
There are 729 drugs known to interact with Phenylephrine HD (hydrocodone / phenylephrine), along with 20 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 231 are major, 495 are moderate, and 3 are minor.
- View all 729 medications that may interact with Phenylephrine HD
- View Phenylephrine HD alcohol/food interactions (1)
- View Phenylephrine HD disease interactions (20)
Most frequently checked interactions
View interaction reports for Phenylephrine HD (hydrocodone / phenylephrine) and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- acetaminophen
- amoxicillin
- aspirin
- Aspirin Low Strength (aspirin)
- atenolol
- Benadryl (diphenhydramine)
- bupropion
- caffeine
- chlorpheniramine
- Chlorpheniramine (Allergy) (chlorpheniramine)
- Dextromethorphan HBr Adult Formula (dextromethorphan)
- doxylamine
- Flexeril (cyclobenzaprine)
- fluoxetine
- guaifenesin
- ibuprofen
- loratadine
- losartan
- melatonin
- omeprazole
- Paracetamol (acetaminophen)
- penicillin v potassium
- phenylephrine
- rosuvastatin
- sertraline
- Tylenol (acetaminophen)
- Vitamin D3 (cholecalciferol)
- warfarin
- Zyrtec (cetirizine)
Phenylephrine HD alcohol/food interactions
There is 1 alcohol/food interaction with Phenylephrine HD (hydrocodone / phenylephrine).
Phenylephrine HD disease interactions
There are 20 disease interactions with Phenylephrine HD (hydrocodone / phenylephrine) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
Report options
More about Phenylephrine HD (hydrocodone / phenylephrine)
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.