Hycofenix Interactions
There are 728 drugs known to interact with Hycofenix (guaifenesin/hydrocodone/pseudoephedrine), along with 22 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 221 are major, 501 are moderate, and 6 are minor.
- View all 728 medications that may interact with Hycofenix
- View Hycofenix alcohol/food interactions (1)
- View Hycofenix disease interactions (22)
Most frequently checked interactions
View interaction reports for Hycofenix (guaifenesin / hydrocodone / pseudoephedrine) and the medicines listed below.
- Allegra (fexofenadine)
- Asmanex HFA (mometasone)
- Benadryl (diphenhydramine)
- budesonide nasal
- buspirone
- Claritin (loratadine)
- clonazepam
- cyclobenzaprine
- doxylamine / pyridoxine
- Dramamine (dimenhydrinate)
- Dymista (azelastine / fluticasone nasal)
- famotidine
- Fasenra (benralizumab)
- fluticasone nasal
- modafinil
- Mucinex DM (dextromethorphan / guaifenesin)
- Nurtec ODT (rimegepant)
- omeprazole
- ondansetron
- oxycodone
- prednisone
- ProAir RespiClick (albuterol)
- Promethazine DM (dextromethorphan / promethazine)
- Pulmicort Flexhaler (budesonide)
- sertraline
- sumatriptan
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Ubrelvy (ubrogepant)
- Ventolin HFA (albuterol)
Hycofenix alcohol/food interactions
There is 1 alcohol/food interaction with Hycofenix (guaifenesin / hydrocodone / pseudoephedrine).
Hycofenix disease interactions
There are 22 disease interactions with Hycofenix (guaifenesin / hydrocodone / pseudoephedrine) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
More about Hycofenix (guaifenesin / hydrocodone / pseudoephedrine)
- Hycofenix consumer information
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.