Drug Interactions between Elspar and tramadol

Alcohol can increase the nervous system side effects of traMADol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traMADol. Do not use more than the recommended dose of traMADol, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Talk to your doctor before using asparaginase Escherichia coli together with ethanol (alcohol). Combining these medications may increase the risk of side effects such as liver damage. You may need more frequent monitoring by your doctor to safely use both medications. Let your doctor know immediately if you develop right upper quadrant pain, increasing abdominal size, fever, swelling, rash, itching, loss of appetite, fatigue, nausea, vomiting, dark urine, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.