Drug interactions between doxycycline and Plan B One-Step
|Plan B One-Step (levonorgestrel)|
Interactions between your drugs
There were no interactions found in our database between doxycycline and Plan B One-Step - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.
- Doxycycline is in the following drug classes: miscellaneous antimalarials, tetracyclines.
- Doxycycline is used to treat the following conditions:
- Anthrax Prophylaxis
- Bacterial Infection
- Bullous Pemphigoid
- Chlamydia Infection
- Cutaneous Bacillus anthracis
- Epididymitis, Sexually Transmitted
- Gonococcal Infection, Uncomplicated
- Granuloma Inguinale
- Inclusion Conjunctivitis
- Lyme Disease
- Lyme Disease, Arthritis
- Lyme Disease, Carditis
- Lyme Disease, Erythema Chronicum Migrans
- Lyme Disease, Neurologic
- Lymphogranuloma Venereum
- Malaria Prevention
- Mycoplasma Pneumonia
- Nongonococcal Urethritis
- Ocular Rosacea
- Pelvic Inflammatory Disease
- Pleural Effusion
- Q Fever
- Rabbit Fever
- Rheumatoid Arthritis
- Rickettsial Infection
- Skin or Soft Tissue Infection
- STD Prophylaxis
- Syphilis, Early
- Syphilis, Latent
- Tertiary Syphilis
- Upper Respiratory Tract Infection
- Urinary Tract Infection
Plan B One-Step
- Plan B One-Step is a member of the following drug classes: contraceptives, progestins.
- Plan B One-Step is used to treat Emergency Contraception.
Drug and food interactions
Applies to: Plan B One-Step (levonorgestrel)
Consumer information for this interaction is not currently available.
MONITOR: Grapefruit juice may increase the plasma concentrations of orally administered drugs that are substrates of the CYP450 3A4 isoenzyme. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruit. Because grapefruit juice inhibits primarily intestinal rather than hepatic CYP450 3A4, the magnitude of interaction is greatest for those drugs that undergo significant presystemic metabolism by CYP450 3A4 (i.e., drugs with low oral bioavailability). In general, the effect of grapefruit juice is concentration-, dose- and preparation-dependent, and can vary widely among brands. Certain preparations of grapefruit juice (e.g., high dose, double strength) have sometimes demonstrated potent inhibition of CYP450 3A4, while other preparations (e.g., low dose, single strength) have typically demonstrated moderate inhibition. Pharmacokinetic interactions involving grapefruit juice are also subject to a high degree of interpatient variability, thus the extent to which a given patient may be affected is difficult to predict.
MANAGEMENT: Patients who regularly consume grapefruit or grapefruit juice should be monitored for adverse effects and altered plasma concentrations of drugs that undergo significant presystemic metabolism by CYP450 3A4. Grapefruit and grapefruit juice should be avoided if an interaction is suspected. Orange juice is not expected to interact with these drugs.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.