Diphenhydramine/hydrocodone/phenylephrine Interactions
There are 787 drugs known to interact with diphenhydramine/hydrocodone/phenylephrine, along with 28 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 237 are major, 546 are moderate, and 4 are minor.
- View all 787 medications that may interact with diphenhydramine/hydrocodone/phenylephrine
- View diphenhydramine/hydrocodone/phenylephrine alcohol/food interactions (1)
- View diphenhydramine/hydrocodone/phenylephrine disease interactions (28)
Most frequently checked interactions
View interaction reports for diphenhydramine / hydrocodone / phenylephrine and the medicines listed below.
- Acidophilus (lactobacillus acidophilus)
- Acidophilus (lactobacillus acidophilus)
- Actos (pioglitazone)
- Actos (pioglitazone)
- Adcetris (brentuximab)
- Adcetris (brentuximab)
- Advil (ibuprofen)
- Advil (ibuprofen)
- Ambien (zolpidem)
- Ambien (zolpidem)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- Celebrex (celecoxib)
- Celexa (citalopram)
- Celexa (citalopram)
- Klonopin (clonazepam)
- Klonopin (clonazepam)
- Lexapro (escitalopram)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xanax (alprazolam)
Diphenhydramine/hydrocodone/phenylephrine alcohol/food interactions
There is 1 alcohol/food interaction with diphenhydramine / hydrocodone / phenylephrine.
Diphenhydramine/hydrocodone/phenylephrine disease interactions
There are 28 disease interactions with diphenhydramine / hydrocodone / phenylephrine which include:
- depression
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
Report options
More about diphenhydramine / hydrocodone / phenylephrine
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.