Dextromethorphan/guaifenesin/pseudoephedrine Interactions
There are 477 drugs known to interact with dextromethorphan/guaifenesin/pseudoephedrine, along with 6 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 79 are major, 392 are moderate, and 6 are minor.
- View all 477 medications that may interact with dextromethorphan/guaifenesin/pseudoephedrine
- View dextromethorphan/guaifenesin/pseudoephedrine alcohol/food interactions (1)
- View dextromethorphan/guaifenesin/pseudoephedrine disease interactions (6)
Most frequently checked interactions
View interaction reports for dextromethorphan / guaifenesin / pseudoephedrine and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- Acidophilus (lactobacillus acidophilus)
- Acidophilus Probiotic Blend (lactobacillus acidophilus)
- Aciphex (rabeprazole)
- Active Carbon (charcoal)
- Actonel (risedronate)
- Advil (ibuprofen)
- Afluria Quadrivalent (influenza virus vaccine, inactivated)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Alka-Seltzer Plus Maximum Strength Cold & Cough (acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine)
- Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Liquid Gels (Night Formula) (acetaminophen / dextromethorphan / doxylamine / phenylephrine)
- Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels (acetaminophen / dextromethorphan / phenylephrine)
- Allegra (fexofenadine)
- Allegra-D 24 Hour Allergy & Congestion (fexofenadine / pseudoephedrine)
- Almacone (aluminum hydroxide / magnesium hydroxide / simethicone)
- Ambien (zolpidem)
- Amrix (cyclobenzaprine)
- Benadryl (diphenhydramine)
- Celexa (citalopram)
- Crestor (rosuvastatin)
- Depakote (divalproex sodium)
- Dilaudid (hydromorphone)
- Flexeril (cyclobenzaprine)
- Lotrel (amlodipine / benazepril)
- Norflex (orphenadrine)
- Penicillin VK (penicillin v potassium)
- Pepto-Bismol (bismuth subsalicylate)
- Prilosec (omeprazole)
- ProAir HFA (albuterol)
- Vicks NyQuil Cold & Flu Nighttime Relief (acetaminophen / dextromethorphan / doxylamine)
Dextromethorphan/guaifenesin/pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with dextromethorphan / guaifenesin / pseudoephedrine.
Dextromethorphan/guaifenesin/pseudoephedrine disease interactions
There are 6 disease interactions with dextromethorphan / guaifenesin / pseudoephedrine which include:
Report options
More about dextromethorphan / guaifenesin / pseudoephedrine
- dextromethorphan/guaifenesin/pseudoephedrine consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (10)
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
