Dextromethorphan/guaifenesin/pseudoephedrine Interactions
There are 527 drugs known to interact with dextromethorphan/guaifenesin/pseudoephedrine, along with 6 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 88 are major, 432 are moderate, and 7 are minor.
- View all 527 medications that may interact with dextromethorphan/guaifenesin/pseudoephedrine
- View dextromethorphan/guaifenesin/pseudoephedrine alcohol/food interactions (1)
- View dextromethorphan/guaifenesin/pseudoephedrine disease interactions (6)
Most frequently checked interactions
View interaction reports for dextromethorphan / guaifenesin / pseudoephedrine and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- Acidophilus (lactobacillus acidophilus)
- Acidophilus Probiotic Blend (lactobacillus acidophilus)
- Aciphex (rabeprazole)
- Active Carbon (charcoal)
- Actonel (risedronate)
- Advil (ibuprofen)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil PM (diphenhydramine / ibuprofen)
- Afluria Quadrivalent (influenza virus vaccine, inactivated)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve PM (diphenhydramine / naproxen)
- Alka-Seltzer Plus Maximum Strength Cold & Cough (acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine)
- Allegra (fexofenadine)
- Ativan (lorazepam)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- Celexa (citalopram)
- Crestor (rosuvastatin)
- Depakote (divalproex sodium)
- Dilaudid (hydromorphone)
- Flexeril (cyclobenzaprine)
- Lotrel (amlodipine / benazepril)
- Norflex (orphenadrine)
- Penicillin VK (penicillin v potassium)
- Pepto-Bismol (bismuth subsalicylate)
- Prilosec (omeprazole)
- ProAir HFA (albuterol)
- Vicks NyQuil Cold & Flu Nighttime Relief (acetaminophen / dextromethorphan / doxylamine)
- Vitamin D3 (cholecalciferol)
Dextromethorphan/guaifenesin/pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with dextromethorphan / guaifenesin / pseudoephedrine.
Dextromethorphan/guaifenesin/pseudoephedrine disease interactions
There are 6 disease interactions with dextromethorphan / guaifenesin / pseudoephedrine which include:
Report options
More about dextromethorphan / guaifenesin / pseudoephedrine
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- Compare alternatives
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- Reviews (10)
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Promethazine VC with Codeine
Promethazine VC with Codeine is used for cough and nasal congestion
Mucinex D
Mucinex D (guaifenesin and pseudoephedrine) is used to treat nasal and sinus congestion, and to ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Vicks Nyquil Cough
Vicks Nyquil Cough is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.