Polytussin DM Interactions
There are 570 drugs known to interact with Polytussin DM (dexchlorpheniramine / dextromethorphan / phenylephrine), along with 8 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 94 are major, 473 are moderate, and 3 are minor.
- View all 570 medications that may interact with Polytussin DM
- View Polytussin DM alcohol/food interactions (2)
- View Polytussin DM disease interactions (8)
Most frequently checked interactions
View interaction reports for Polytussin DM (dexchlorpheniramine / dextromethorphan / phenylephrine) and the medicines listed below.
- acetaminophen
- acetaminophen
- amoxicillin / clavulanate
- amoxicillin / clavulanate
- atorvastatin
- atorvastatin
- azelastine nasal
- azelastine nasal
- azithromycin
- azithromycin
- Claritin (loratadine)
- Claritin (loratadine)
- doxycycline
- doxycycline
- gabapentin
- gabapentin
- hydroxychloroquine
- hydroxychloroquine
- ibuprofen
- ibuprofen
- methocarbamol
- methocarbamol
- prednisone
- prednisone
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
- Wellbutrin XL (bupropion)
- Zofran (ondansetron)
- Zofran (ondansetron)
Polytussin DM alcohol/food interactions
There are 2 alcohol/food interactions with Polytussin DM (dexchlorpheniramine / dextromethorphan / phenylephrine).
Polytussin DM disease interactions
There are 8 disease interactions with Polytussin DM (dexchlorpheniramine / dextromethorphan / phenylephrine) which include:
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- BPH
- diabetes
- glaucoma
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.