Codeine/phenylephrine/promethazine Interactions
There are 819 drugs known to interact with codeine/phenylephrine/promethazine, along with 33 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 216 are major, 591 are moderate, and 12 are minor.
- View all 819 medications that may interact with codeine/phenylephrine/promethazine
- View codeine/phenylephrine/promethazine alcohol/food interactions (3)
- View codeine/phenylephrine/promethazine disease interactions (33)
Most frequently checked interactions
View interaction reports for codeine / phenylephrine / promethazine and the medicines listed below.
- Abilify (aripiprazole)
- Aceta w / Codeine (acetaminophen / codeine)
- Acidophilus (lactobacillus acidophilus)
- Acticlate (doxycycline)
- Adderall (amphetamine / dextroamphetamine)
- Advil Migraine (ibuprofen)
- Afrin (oxymetazoline nasal)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve (naproxen)
- Aspirin Low Strength (aspirin)
- Augmentin (amoxicillin / clavulanate)
- Azithromycin Dose Pack (azithromycin)
- Benadryl (diphenhydramine)
- Cialis (tadalafil)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Lexapro (escitalopram)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Norco (acetaminophen / hydrocodone)
- Pepto-Bismol (bismuth subsalicylate)
- Premarin (conjugated estrogens)
- Saline Nasal Mist (sodium chloride nasal)
- Tylenol (acetaminophen)
- Tylenol Sinus Congestion & Pain Nighttime (acetaminophen / chlorpheniramine / phenylephrine)
- Valium (diazepam)
- Viagra (sildenafil)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zinc (zinc sulfate)
Codeine/phenylephrine/promethazine alcohol/food interactions
There are 3 alcohol/food interactions with codeine / phenylephrine / promethazine.
Codeine/phenylephrine/promethazine disease interactions
There are 33 disease interactions with codeine / phenylephrine / promethazine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
- BPH
- diabetes
- glaucoma
Report options
More about codeine / phenylephrine / promethazine
- codeine/phenylephrine/promethazine consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Ozempic
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Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Vicks Nyquil Cough
Vicks Nyquil Cough is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.