Cobicistat/darunavir/emtricitabine/tenofovir alafenamide Interactions
There are 774 drugs known to interact with cobicistat/darunavir/emtricitabine/tenofovir alafenamide, along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 346 are major, 405 are moderate, and 23 are minor.
- View cobicistat/darunavir/emtricitabine/tenofovir alafenamide alcohol/food interactions (2)
- View cobicistat/darunavir/emtricitabine/tenofovir alafenamide disease interactions (11)
Medications known to interact with cobicistat/darunavir/emtricitabine/tenofovir alafenamide
Note: Showing generic names only.
A
- abacavir
- abametapir topical
- abemaciclib
- abiraterone
- abrocitinib
- acalabrutinib
- acarbose
- acetohexamide
- acyclovir
- adagrasib
- adalimumab
- adefovir
- ado-trastuzumab emtansine
- afatinib
- albendazole
- albiglutide
- aldesleukin
- alefacept
- alfentanil
- alfuzosin
- aliskiren
- almotriptan
- alogliptin
- alpelisib
- alprazolam
- ambrisentan
- amikacin
- amikacin liposome
- amiloride
- aminoglutethimide
- amiodarone
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amphetamine
- amphotericin b
- amphotericin b cholesteryl sulfate
- amphotericin b lipid complex
- amphotericin b liposomal
- amprenavir
- anakinra
- anisindione
- apalutamide
- apixaban
- aprepitant
- aripiprazole
- armodafinil
- artesunate
- asciminib
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atazanavir
- atidarsagene autotemcel
- atogepant
- atomoxetine
- atorvastatin
- atrasentan
- avacopan
- avanafil
- avapritinib
- avatrombopag
- axitinib
- aztreonam
B
- bacitracin
- balsalazide
- bedaquiline
- belzutifan
- benzgalantamine
- bepridil
- berotralstat
- betamethasone
- betiatide
- betibeglogene autotemcel
- betrixaban
- bexagliflozin
- bexarotene
- bimekizumab
- binimetinib
- black cohosh
- boceprevir
- bortezomib
- bosentan
- bosutinib
- botulism immune globulin
- brentuximab
- brexpiprazole
- brigatinib
- brincidofovir
- brodalumab
- bromfenac
- bromocriptine
- budesonide
- budesonide nasal
- buprenorphine
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabozantinib
- calaspargase pegol
- canagliflozin
- canakinumab
- cannabidiol
- cannabis
- capivasertib
- capmatinib
- capreomycin
- carbamazepine
- carboplatin
- cariprazine
- carvedilol
- cat's claw
- celecoxib
- cenobamate
- ceritinib
- cerivastatin
- cevimeline
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- chloroquine
- chlorotrianisene
- chlorpheniramine
- chlorpromazine
- chlorpropamide
- ciclesonide
- ciclesonide nasal
- cidofovir
- cilostazol
- cimetidine
- cinacalcet
- cisapride
- cisplatin
- citalopram
- cladribine
- clarithromycin
- clindamycin
- clofarabine
- clomipramine
- clonazepam
- clopidogrel
- clorazepate
- clotrimazole
- clozapine
- cobimetinib
- codeine
- colchicine
- colistimethate
- conivaptan
- conjugated estrogens
- conjugated estrogens topical
- copanlisib
- cortisone
- crizotinib
- cyclophosphamide
- cyclosporine
- cytomegalovirus immune globulin
D
- dabigatran
- dabrafenib
- daclatasvir
- daclizumab
- danicopan
- dapagliflozin
- daridorexant
- darifenacin
- darolutamide
- dasatinib
- deferasirox
- deferoxamine
- deflazacort
- dehydroepiandrosterone
- delavirdine
- desipramine
- dexamethasone
- dexamethasone nasal
- dexamethasone ophthalmic
- dexfenfluramine
- dextroamphetamine
- dextromethorphan
- diatrizoate
- diazepam
- diclofenac
- dicumarol
- didanosine
- dienestrol topical
- diflunisal
- digoxin
- dihydroergotamine
- diltiazem
- dimethyl fumarate
- diphenhydramine
- diroximel fumarate
- disopyramide
- docetaxel
- dofetilide
- dolutegravir
- donepezil
- doravirine
- doxazosin
- doxepin
- doxorubicin
- doxorubicin liposomal
- dronedarone
- droperidol
- drospirenone
- dulaglutide
- duloxetine
- dutasteride
- duvelisib
E
- echinacea
- edetate calcium disodium
- edetate disodium (edta)
- edoxaban
- efavirenz
- elacestrant
- elafibranor
- elagolix
- eletriptan
- eliglustat
- elivaldogene autotemcel
- eluxadoline
- emapalumab
- empagliflozin
- encorafenib
- enfortumab vedotin
- enfuvirtide
- entrectinib
- enzalutamide
- epirubicin
- eplerenone
- eravacycline
- erdafitinib
- ergonovine
- ergotamine
- eribulin
- erlotinib
- ertugliflozin
- erythromycin
- escitalopram
- eslicarbazepine
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethinyl estradiol
- ethosuximide
- etidronate
- etodolac
- etonogestrel
- etoposide
- etranacogene dezaparvovec
- etrasimod
- etravirine
- everolimus
- exenatide
- ezetimibe
F
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fenoprofen
- fentanyl
- fesoterodine
- fexinidazole
- fidanacogene elaparvovec
- fidaxomicin
- finerenone
- flecainide
- flibanserin
- fluconazole
- flucytosine
- fludrocortisone
- flunisolide
- flunisolide nasal
- fluorometholone ophthalmic
- fluoxetine
- fluphenazine
- flurazepam
- flurbiprofen
- fluticasone
- fluticasone nasal
- fluvastatin
- fluvoxamine
- fosamprenavir
- fosaprepitant
- foscarnet
- fosphenytoin
- fostamatinib
- fostemsavir
- futibatinib
G
- galantamine
- gallium nitrate
- ganaxolone
- ganciclovir
- gefitinib
- gentamicin
- gepirone
- gilteritinib
- givinostat
- givosiran
- glasdegib
- glimepiride
- glipizide
- glofitamab
- glyburide
- golimumab
- granisetron
- griseofulvin
- guanfacine
- guselkumab
H
- halofantrine
- haloperidol
- halothane
- hydrocodone
- hydrocortisone
- hydroxychloroquine
- hydroxyprogesterone
I
- ibandronate
- ibrexafungerp
- ibrutinib
- ibuprofen
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imipramine
- immune globulin intravenous
- immune globulin intravenous and subcutaneous
- indacaterol
- indinavir
- indomethacin
- infigratinib
- infliximab
- inotersen
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- interferon beta-1a
- interferon beta-1b
- iobenguane I 131
- iodamide
- iodipamide
- iodixanol
- iohexol
- iomeprol
- iopamidol
- iopromide
- iothalamate
- ioversol
- ioxaglate
- ioxilan
- iptacopan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isoniazid
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivermectin
- ivosidenib
- ixabepilone
K
L
- lacosamide
- lamivudine
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- leniolisib
- lesinurad
- letermovir
- letrozole
- levacetylleucine
- levamlodipine
- levobupivacaine
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levonorgestrel
- lidocaine
- lifileucel
- linagliptin
- liraglutide
- lisdexamfetamine
- lithium
- lixisenatide
- lomitapide
- lonafarnib
- lonapegsomatropin
- loperamide
- loratadine
- lorlatinib
- loteprednol ophthalmic
- lovastatin
- lovotibeglogene autotemcel
- lumateperone
- lurasidone
- lurbinectedin
- lusutrombopag
- lutetium lu 177 dotatate
- lutetium lu 177 vipivotide tetraxetan
M
- macitentan
- maprotiline
- maraviroc
- maribavir
- mavacamten
- mavorixafor
- meclofenamate
- medroxyprogesterone
- mefenamic acid
- mefloquine
- megestrol
- meloxicam
- memantine
- mephobarbital
- mesalamine
- metformin
- methadone
- methamphetamine
- methotrexate
- methotrimeprazine
- methoxyflurane
- methylergonovine
- methylprednisolone
- methysergide maleate
- metoclopramide
- metoprolol
- metrizamide
- mexiletine
- mibefradil
- miconazole
- midazolam
- midodrine
- midostaurin
- mifepristone
- miglitol
- mipomersen
- mirabegron
- mirtazapine
- mirvetuximab soravtansine
- mitapivat
- mitotane
- mobocertinib
- modafinil
- momelotinib
- mometasone
- mometasone nasal
- monomethyl fumarate
- morphine
- moxetumomab pasudotox
N
- nabumetone
- nafcillin
- naldemedine
- naloxegol
- naltrexone
- naproxen
- nateglinide
- nebivolol
- nelfinavir
- nemolizumab
- neomycin
- neratinib
- netilmicin
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nimodipine
- nintedanib
- niraparib
- nirogacestat
- nisoldipine
- nitisinone
- norethindrone
- norgestrel
- nortriptyline
O
- olaparib
- oliceridine
- olsalazine
- olutasidenib
- omaveloxolone
- ondansetron
- oritavancin
- orlistat
- osilodrostat
- osimertinib
- ospemifene
- oteseconazole
- oxaliplatin
- oxaprozin
- oxcarbazepine
- oxybutynin
- oxycodone
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- palovarotene
- pamidronate
- panobinostat
- paricalcitol
- paroxetine
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pemetrexed
- pemigatinib
- penicillamine
- pentamidine
- pentobarbital
- perphenazine
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pimavanserin
- pimecrolimus topical
- pimozide
- pindolol
- pioglitazone
- piroxicam
- pirtobrutinib
- pitavastatin
- pitolisant
- plazomicin
- polatuzumab vedotin
- polymyxin b
- pomalidomide
- ponatinib
- porfimer
- posaconazole
- pralsetinib
- pramlintide
- pravastatin
- praziquantel
- prednisolone
- prednisolone ophthalmic
- prednisone
- pretomanid
- primidone
- procainamide
- prochlorperazine
- progesterone
- progesterone topical
- promethazine
- propafenone
- propoxyphene
- propranolol
- protriptyline
- prucalopride
Q
R
- raltegravir
- ramelteon
- ranitidine
- ranitidine bismuth citrate
- ranolazine
- red yeast rice
- regorafenib
- relugolix
- remdesivir
- repaglinide
- repotrectinib
- resmetirom
- respiratory syncytial virus immune globulin
- retapamulin topical
- revefenacin
- revumenib
- rho (d) immune globulin
- ribavirin
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- rilpivirine
- rimegepant
- riociguat
- ripretinib
- risperidone
- ritlecitinib
- ritonavir
- rivaroxaban
- rizatriptan
- rofecoxib
- roflumilast topical
- romidepsin
- ropivacaine
- rosiglitazone
- rosuvastatin
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- salmeterol
- salsalate
- saquinavir
- sarecycline
- sarilumab
- satralizumab
- saxagliptin
- secobarbital
- secukinumab
- seladelpar
- selpercatinib
- selumetinib
- semaglutide
- sertraline
- sibutramine
- sildenafil
- silodosin
- siltuximab
- simeprevir
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- sirolimus topical
- sitagliptin
- sofpironium topical
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sonidegib
- sotagliflozin
- sotorasib
- sparsentan
- st. john's wort
- stavudine
- stiripentol
- streptomycin
- streptozocin
- sufentanil
- sulfasalazine
- sulfinpyrazone
- sulindac
- sunitinib
- suvorexant
- suzetrigine
T
- tacrolimus
- tacrolimus topical
- tadalafil
- tafamidis
- talazoparib
- tamoxifen
- tamsulosin
- tasimelteon
- tazemetostat
- tecovirimat
- telaprevir
- telavancin
- telbivudine
- telithromycin
- telotristat
- temsirolimus
- teniposide
- tepotinib
- terfenadine
- teriflunomide
- testosterone
- testosterone topical
- tetrabenazine
- thioguanine
- thioridazine
- thiotepa
- tiagabine
- ticagrelor
- timolol
- tinidazole
- tipranavir
- tirzepatide
- tisotumab vedotin
- tobramycin
- tocilizumab
- tofacitinib
- tolazamide
- tolbutamide
- tolmetin
- tolterodine
- tolvaptan
- toremifene
- tovorafenib
- trabectedin
- tramadol
- trazodone
- treosulfan
- tretinoin
- triamcinolone
- triamcinolone nasal
- triamcinolone ophthalmic
- triamterene
- triazolam
- trimipramine
- trofinetide
- troglitazone
- troleandomycin
- trospium
- tucatinib
U
V
- vadadustat
- valacyclovir
- valbenazine
- valdecoxib
- valganciclovir
- valoctocogene roxaparvovec
- vamorolone
- vancomycin
- vardenafil
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vibegron
- vilazodone
- viloxazine
- vimseltinib
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vorapaxar
- vorasidenib
- voriconazole
- voxelotor
W
Z
- zalcitabine
- zanubrutinib
- zavegepant
- zidovudine
- ziprasidone
- zoledronic acid
- zolpidem
- zonisamide
- zuranolone
Cobicistat/darunavir/emtricitabine/tenofovir alafenamide alcohol/food interactions
There are 2 alcohol/food interactions with cobicistat / darunavir / emtricitabine / tenofovir alafenamide.
Cobicistat/darunavir/emtricitabine/tenofovir alafenamide disease interactions
There are 11 disease interactions with cobicistat / darunavir / emtricitabine / tenofovir alafenamide which include:
- hepatotoxicity
- hepatitis B
- hepatotoxicity
- creatinine clearance
- hemodialysis
- renal dysfunction
- hemophilia
- hyperglycemia
- bone toxicity
- liver disease
- renal dysfunction
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- Drug class: antiviral combinations
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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